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Tolterodine
go.drugbank.com/drugs/DB01036ApprovedInvestigationalTolterodine is an antimuscarinic drug that is used to treat urinary incontinence. Tolterodine acts on M2 and M3 subtypes of muscarinic receptors.
Synonyms: (+)-(R)-2-(alpha-(2-(Diisopropylamino)ethyl)benzyl)-p-cresolCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesCarphenazine
go.drugbank.com/drugs/DB01038ApprovedWithdrawnCarphenazine is an antipsychotic drug, used in hospitalized patients in the management of chronic schizophrenic psychoses.
Categories: Serotonin 5-HT2 Receptor Antagonists, Serotonin 5-HT2A Receptor AntagonistsFenofibrate
go.drugbank.com/drugs/DB01039ApprovedInvestigationalFenofibrate is a fibric acid derivative like [clofibrate] and [gemfibrozil].[A185954] Fenofibrate is used to treat primary hypercholesterolemia, mixed dyslipidemia, severe hypertriglyceridemia.
Synonyms: 2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic acid 1-methylethyl ester, Isopropyl (4'-(p-chlorobenzoyl)-2-phenoxy-2-methyl)propionateMixtures: SIMITRI®145/20MG, PRAVAFEN® CAPSULASThalidomide
go.drugbank.com/drugs/DB01041ApprovedInvestigationalWithdrawnA piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, thalidomide was withdrawn from the market due to teratogenic effects. … It has been reintroduced and used for a number of inflammatory disorders and cancers.
Synonyms: α-N-phthalylglutaramide, (+-)-N-(2,6-dioxo-3-Piperidyl)phthalimideInternational brands: K-17, Pro-ban MMelphalan
go.drugbank.com/drugs/DB01042ApprovedInvestigationalMelphalan is a nitrogen mustard or bischloroethylamine type alkylating agent. … [L40928] It was first synthesized in the early 1950s by substituting L-phenylalanine for the methyl group on nitrogen mustard.
Synonyms: 3-(p-(Bis(2-chloroethyl)amino)phenyl)-L-alanine, 3-p-(Di(2-chloroethyl)amino)-phenyl-L-alanineProducts: ALKERAN® 2 MG TABLETAS, ALKERAN® INYECTABLEGatifloxacin
go.drugbank.com/drugs/DB01044ApprovedInvestigationalWithdrawnIt is also available as eye drops under the brand name Zymar® marketed by Allergan. … It was first introduced by Bristol-Myers Squibb in 1999 under the brand name Tequin® for the treatment of respiratory tract infections.
Synonyms: 1-Cyclopropyl-1,4-dihydro-6-fluoro-8-methoxy-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro- 8-methoxy-7-(3-methylpiperazin-1-yl)- 4-oxo-quinoline-3-carboxylic acidMixtures: CARTEOF®, NORIGRAN®Rifampin
go.drugbank.com/drugs/DB01045ApprovedInvestigationalRifampin, also known as rifampicin, is a broad-spectrum antimicrobial [A263748] that was first discovered in 1965 [A263753] and clinically used in 1968.
Synonyms: 3-(((4-Methyl-1-piperazinyl)imino)methyl)rifamycin SV, 5,6,9,17,19,21-Hexahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-8-[N-(4-methyl-1-piperazinyl)formimidoyl]-2,7-(epoxypentadeca[1,11,13]trienimino)naphtho[2,1-b]furan-1,11(2H)-dione 21-acetateMixtures: RINCURE ® 3 FDC TABLETAS CON PELICULA, DOTBAL-SLubiprostone
go.drugbank.com/drugs/DB01046ApprovedInvestigationalA prostaglandin E1 derivative, lubiprostone is a bicyclic fatty acid that activates ClC-2 chloride channels located on the apical side of the gastrointestinal epithelial cells. … Lubiprostone is a medication used in the management of idiopathic chronic constipation.
Categories: Prostaglandins EProducts: MOVIPROST ® 8 MCG, อามิทีซา 8 ไมโครกรัมAzlocillin
go.drugbank.com/drugs/DB01061ApprovedAzlocillin is a semisynthetic ampicillin-derived acylureido penicillin.
Synonyms: (2S,5R,6R)-3,3-dimethyl-7-oxo-6-{[(2R)-2-{[(2-oxoimidazolidin-1-yl)carbonyl]amino}-2-phenylacetyl]amino}-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acidCategories: Penicillin G, Heterocyclic Compounds, 2-RingCefditoren
go.drugbank.com/drugs/DB01066ApprovedCefditoren is an oral third-generation cephalosporin. It is commonly marketed under the trade name Spectracef by Cornerstone BioPharma.
Categories: Heterocyclic Compounds, 2-Ring