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Displaying results 7051 - 7060 of 10000 in total
  1. Drug

    Iberdomide

    go.drugbank.com/drugs/DB12101
    Investigational

    [L64055] Iberdomide has shown anti-tumor activity in multiple myeloma cells resistant to lenalidomide and pomalidomide, and as a CELMoD is designed to degrade Ikaros and Aiolos more potently than immunomodulatory … accelerated approval on August 13, 2026, in combination with daratumumab and hyaluronidase-fihj and dexamethasone for adults with multiple myeloma who have received at least one prior line of therapy including a

    Categories: Cytochrome P-450 Substrates, P-glycoprotein substratesSynonyms: (S)-3-(4-((4-(Morpholinomethyl)benzyl)oxy)-1-oxoisoindolin-2-yl)piperidine-2,6-dione, 2,6-Piperidinedione, 3-(1,3-dihydro-4-((4-(4-morpholinylmethyl)phenyl)methoxy)-1-oxo-2H-isoindol-2-yl)-, (3S)-
  2. Drug

    Sultamicillin

    go.drugbank.com/drugs/DB12127
    ApprovedWithdrawn

    Sultamicillin has been used in trials studying the prevention and treatment of Ventilator Associated Pneumonia and Chronic Obstructive Pulmonary Disease (COPD).

    Categories: Penicillin G, Heterocyclic Compounds, 2-RingProducts: BACTESUL 1 G/ 5 ML, BACMICINE® 250 MG / 5 ML
  3. Drug

    Dilmapimod

    go.drugbank.com/drugs/DB12140
    Investigational

    Dilmapimod (SB-681323) is a p38 MAP-kinase inhibitor that has potential uses in inflammatory conditions such as RA (Rheumatoid Arthritis).

    Categories: Heterocyclic Compounds, 1-Ring
  4. Drug

    Itacitinib

    go.drugbank.com/drugs/DB12154
    Investigational

    Itacitinib has been used in trials studying the treatment of Melanoma, Carcinoma, Metastatic Cancer, Endometrial Cancer, and B-cell Malignancies, among others.

    Categories: Heterocyclic Compounds, 1-Ring
  5. Drug

    Beclabuvir

    go.drugbank.com/drugs/DB12225
    Investigational

    Beclabuvir has been used in trials studying the treatment of Hepatitis C, Chronic.

    Categories: Heterocyclic Compounds, 2-Ring
  6. Drug

    Cerlapirdine

    go.drugbank.com/drugs/DB12229
    Investigational

    Cerlapirdine has been investigated for the treatment of Alzheimer Disease.

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring
  7. Drug

    Ecopipam

    go.drugbank.com/drugs/DB12273
    Investigational

    Ecopipam has been used in trials studying the treatment of Tourette's Syndrome, Lesch-Nyhan Disease, Pathological Gambling, and Self-injurious Behavior.

    Categories: Heterocyclic Compounds, 2-Ring
  8. Drug

    Defactinib

    go.drugbank.com/drugs/DB12282
    ApprovedInvestigational

    Defactinib is a small molecule kinase inhibitor targeted against focal adhesion kinase (FAK) and proline-rich tyrosine kinase-2 (Pyk2), the two members of the FAK family of nonreceptor tyrosine kinases … [L53198,L53208] FAK is important for the integrin-mediated activation of several downstream signal transduction pathways, including those involving RAS/MEK/ERK and PI3K/Akt, and its upregulation is a key

    Categories: MATE 2 Inhibitors, Cytochrome P-450 SubstratesSynonyms: N-methyl-4-[[4-[[3-[methyl(methylsulfonyl)amino]pyrazin-2-yl]methylamino]-5-(trifluoromethyl)pyrimidin-2-yl]amino]benzamide
  9. Drug

    Balapiravir

    go.drugbank.com/drugs/DB12283
    Investigational

    Balapiravir has been used in trials studying the treatment of Dengue and Hepatitis C, Chronic.

  10. Drug

    Doravirine

    go.drugbank.com/drugs/DB12301
    ApprovedInvestigational

    treatments available for the management of HIV-1 infection. … Doravirine is an HIV-1 non-nucleoside reverse transcriptase inhibitor (NNRTI) intended to be administered in combination with other antiretroviral medicines.

    Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-Ring