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Dasatinib
go.drugbank.com/drugs/DB01254ApprovedInvestigational[A2226] The use of dasatinib was first approved by the FDA in 2006.[L45171,L45186] … [A2226,A11377] Also, mutations in the kinase domain of BCR-ABL may lead to relapse during imatinib treatment.
Synonyms: N-(2-CHLORO-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamideProducts: DASATINIB EGLeuprolide
go.drugbank.com/drugs/DB00007ApprovedInvestigationalProlonged activation of GnRHR results in significant downregulation of sex steroid levels, which is primarily responsible for the clinical efficacy of leuprolide in diverse conditions, including advanced … [L13781, L13790] Leuprolide remains frontline therapy in all conditions for which it is indicated for use.
Products: ELIGARD 22.5 MG ENJ. COZ. ICIN S.C. TOZ ICEREN SIRINGA VE COZUCU ICEREN SIRINGA, 1 ADETAmiodarone
go.drugbank.com/drugs/DB01118ApprovedInvestigational[A36817] Most known for its approved indication in life-threatening ventricular arrhythmias, it is also used off-label in the outpatient and inpatient setting for atrial fibrillation. … Amiodarone is a benzofuran derivative, anti-arrhythmic drug used commonly in a variety of settings.
Synonyms: 2-n-Butyl-3',5'-diiodo-4'-N-diethylaminoethoxy-3-benzoylbenzofuranProducts: AMIODARONE EGPolyinosinic-polycytidylic acid
go.drugbank.com/drugs/DB16467InvestigationalSynonyms: Polyinosinic-polycytidylic acid complexLevofloxacin
go.drugbank.com/drugs/DB01137ApprovedInvestigational[A31453,A190756] Levofloxacin was first approved by the FDA in 1996, and was approved in Canada and several South American countries soon after.[A190663] … moxifloxacin], is a member of the third generation of fluoroquinolones, colloquially referred to as the "respiratory quinolones" due to improved activity against gram-positive bacteria commonly implicated in
Products: Levofloxacin In 5% Dextrose Injection, LEVOFLOXACINA EGItraconazole
go.drugbank.com/drugs/DB01167ApprovedInvestigational[L50051] Itraconazole was first approved in the US in 1992 [L50056] and is available orally. … While the intravenous formulation of the drug was formerly available, it was discontinued in the US in 2007.[A263232]
Products: ITRACONAZOLO EG, Z-FINBuprenorphine
go.drugbank.com/drugs/DB00921ApprovedIllicitInvestigationalVet approvedThis effect can be beneficial, however, as dose-related side effects such as respiratory depression, sedation, and intoxication also plateau at around 32mg, resulting in a lower risk of overdose compared … Provision of OAT is often combined with education about harm reduction including use of clean needles and injection supplies in an effort to reduce the risks associated with injection drug use which includes
Synonyms: 2-(N-cyclopropylmethyl-4,5α-epoxy-3-hydroxy-6-methoxy-6,14-endo-ethanomorphinan-6α-yl)-3,3-dimethyl-2-butanolMixtures: BUPRENORFINA E NALOXONE ETHYPHARM, BUPRENORFINA E NALOXONE ETHYPHARMTeicoplanin
go.drugbank.com/drugs/DB06149ApprovedInvestigationalWithdrawnAll teicoplanins share a same glycopeptide core, teicoplanin A3-1, but differ in the length and conformation of side chains attached to their β-D-glucosamine moiety.
Products: TEICOPLANINA SUNMetronidazole
go.drugbank.com/drugs/DB00916ApprovedInvestigationalIt is available in capsule form, tablet form, and topical form, and suppository preparations for the treatment of various infections. … [A181036,A181039] Metronidazole has been used as an antibiotic for several decades[L7429], with added antiparasitic properties that set it apart from many other antibacterial drugs, allowing it to treat
Mixtures: METARSAL N CAPSULAS, FUROTIL-N (METRONIDAZOL 600MG NIFUROXAZIDE 200MG)Products: BRAUN METRONIDAZOLE INTRAVENOUS INFUSION 500MG IN 100ML PLASTIC CONTAINER, Flagyl ERPhenytoin
go.drugbank.com/drugs/DB00252ApprovedInvestigationalVet approved[A188826,A188832] Clinicians are advised to initiate therapeutic drug monitoring in patients who require phenytoin since even small deviations from the recommended therapeutic range can lead to suboptimal … [A189219,A35884] Both parenteral and oral formulations of phenytoin are available on the market.[A189219]
Mixtures: GAMIBETAL COMPLEXProducts: Phenytoin ER