Teicoplanin is a glycopeptide antibiotic with a similar mechanism of action and spectrum of activity to vancomycin used to treat various infections caused by gram-positive bacteria. Teicoplanin is a glycopeptide antibiotic consisting of a mixture of several compounds, five major (named teicoplanin A2-1 through A2-5) and four minor (named teicoplanin RS-1 through RS-4).
- Mechanism
- Curator reviewed
Teicoplanin inhibits peptidoglycan polymerization, resulting in inhibition of bacterial cell wall synthesis and cell death.
- Primary indication
- For the treatment of bacterial infections caused by susceptible microorganisms.Curator reviewed · 18 structured indications
- Formula / weight
- C88H97Cl2N9O33 · 1879.67 g/mol (avg)
- Also known as
- Teichomycin A2
- Code names
- Antibiotic 8327A · Antibiotic MDL 507 · MDL-507
Resolves to
BJNLLBUOHPVGFT-CAYRISATSA-NSMILESCCCCCCCCCC(=O)N[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1=C2OC3=C(Cl)C=C(C=C3)[C@@H](O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3NC(C)=O)[C@@H]3NC(=O)[C@H](NC(=O)[C@@H]4NC(=O)[C@H]5NC(=O)[C@@H](CC6=CC=C(OC1=CC4=C2)C(Cl)=C6)NC(=O)[C@H](N)C1=CC=C(O)C(OC2=CC(O)=CC5=C2)=C1)C1=CC=C(O)C(=C1)C1=C(C=C(O)C=C1OC1O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]1O)[C@H](NC3=O)C(O)=OWhat you can answer from here — as of March 06, 2025
Which other approved drugs treat the same conditions as Teicoplanin, and which companies have late-stage candidates in those indications?
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