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Aldafermin
go.drugbank.com/drugs/DB16086InvestigationalAldafermin is under investigation in clinical trial NCT03912532 (Evaluation of Efficacy, Safety and Tolerability of Aldafermin in a Phase 2b, Randomized, Double-blind, Placebo-controlled, Multi-center … Study in Subjects With Nonalcoholic Steatohepatitis and Stage 2/3 Fibrosis (ALPINE 2/3)).
Synonyms: (phe5>met,ser6>arg,ala8>ser,gly9>ser,his11>leu) fibroblast growth factor 19 (human fgf19) (5-194)-peptide, produced in escherichia coliLortalamine
go.drugbank.com/drugs/DB09187ExperimentalThis drug never made it past clinical trials, likely due to ocular toxicity in animals, but has been used in positron emission tomography studies to label norepinephrine transporters. … Lortalamine (LM-1404) is a selective norepinephrine reuptake inhibitor developed in the 1980s.
PF-04620110
go.drugbank.com/drugs/DB14887InvestigationalPF-04620110 is under investigation in clinical trial NCT01146327 (A Multiple Dose Study Of PF-04620110 In Healthy Overweight Or Obese Subjects).
Spartalizumab
go.drugbank.com/drugs/DB14892InvestigationalSpartalizumab is under investigation in clinical trial NCT02605967 (Safety and Efficacy Study of PDR001 in Patients With Recurrent or Metastatic Nasopharyngeal Carcinoma).
Modipafant
go.drugbank.com/drugs/DB16237InvestigationalModipafant is under investigation in clinical trial NCT02569827 (Celgosivir or Modipafant as Treatment for Adult Participants With Uncomplicated Dengue Fever in Singapore).
Bemnifosbuvir
go.drugbank.com/drugs/DB19050InvestigationalBemnifosbuvir is under investigation in clinical trial NCT05629962 (SUNRISE-3: Efficacy and Safety of Bemnifosbuvir in High-risk Outpatients With COVID-19).
Synonyms: N-((p(s),2'r)-2-amino-2'-deoxy-2'-fluoro-n,2'-dimethyl-p-phenyl-5'-adenylyl)-l-alanine 1-methylethyl ester, L-alanine, n-((p(s),2'r)-2-amino-2'-deoxy-2'-fluoro-n,2'-dimethyl-p-phenyl-5'-adenylyl)-, 1-methylethyl esterBazlitoran
go.drugbank.com/drugs/DB14990InvestigationalBazlitoran is under investigation in clinical trial NCT02092909 (Phase 1/2 Dose Escalation Study in Patients With Relapsed or Refractory Waldenstrom's Macroglobulinemia).
Olorinab
go.drugbank.com/drugs/DB14998InvestigationalOlorinab is under investigation in clinical trial NCT03155945 (Tolerability, Pharmacokinetics, and Efficacy of APD371 in Subjects With Crohn's Disease Experiencing Abdominal Pain).
Tavolixizumab
go.drugbank.com/drugs/DB15042InvestigationalTavolixizumab is under investigation in clinical trial NCT02318394 (A Phase 1 Study of MEDI0562 in Adult Subjects With Selected Advanced Solid Tumors).