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Foselutoclax
go.drugbank.com/drugs/DB21663InvestigationalFoselutoclax is a small molecule drug. The usage of the INN stem '-toclax' in the name indicates that Foselutoclax is a B-cell lymphoma 2 (Bcl-2) inhibitor. … Foselutoclax is under investigation in clinical trial NCT06011798 (Assess the Efficacy and Safety of Repeat Intravitreal Injections of Foselutoclax (UBX1325) in Patients With DME (ASPIRE)).
Olomorasib
go.drugbank.com/drugs/DB21697InvestigationalOlomorasib is under investigation in clinical trial NCT06890598 (Study of Olomorasib (LY3537982) in Combination With Standard of Care in Participants With Resected or Unresectable KRAS G12C-mutant Non-Small … Olomorasib is a small molecule drug. The usage of the INN stem '-rasib' in the name indicates that Olomorasib is a Ras protein inhibitor.
SYNB1353
go.drugbank.com/drugs/DB17666InvestigationalIt is designed to consume methionine in the gastrointestinal tract to prevent its absorption and conversion into homocysteine.[L45983] … [A258833] Developed by Synlogic Operating Company, Inc., SYNB1353 is being investigated for the treatment of homocystinuria.
Bremzalerbart
go.drugbank.com/drugs/DB19417InvestigationalBremzalerbart is under investigation in clinical trial NCT06602739 (A Study to Demonstrate the Effect of REGN5713-5715 on Reducing Ocular Allergy Signs and Symptoms in Adult Participants With Birch Pollen
Atisnolerbart
go.drugbank.com/drugs/DB19418InvestigationalAtisnolerbart is under investigation in clinical trial NCT06602739 (A Study to Demonstrate the Effect of REGN5713-5715 on Reducing Ocular Allergy Signs and Symptoms in Adult Participants With Birch Pollen
Zavacorilant
go.drugbank.com/drugs/DB21509InvestigationalZavacorilant is under investigation in clinical trial NCT04672512 (Single and Multiple Ascending Dose Study of CORT125329 in Healthy Participants). … Zavacorilant is a small molecule drug. The usage of the INN stem '-corilant' in the name indicates that Zavacorilant is a glucocorticoid receptor antagonist (non-steroidal).
Xiliertinib
go.drugbank.com/drugs/DB21453InvestigationalXiliertinib is under investigation in clinical trial NCT02601274 (Study of Theliatinib (HMPL-309) in Patients With Advanced Solid Tumor). Xiliertinib has a monoisotopic molecular weight of 442.21 Da. … Xiliertinib is a small molecule drug. The usage of the INN stem '-ertinib' in the name indicates that Xiliertinib is a epidermal growth factor receptor (EGFR) inhibitor.