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Metoclopramide
go.drugbank.com/drugs/DB01233ApprovedInvestigationalDiabetic gastroparesis is a condition that causes frequent nausea and vomiting, which has a negative impact on quality of life and poses a significant burden on the healthcare system. … [A184934] Metoclopramide is a dopamine antagonist used to treat nausea and vomiting that may be associated with diabetic gastroparesis in addition to gastroesophageal reflux disease (GERD).
Mixtures: CLIFAR® GOTAS, PLASIL®ENZIMATICOCategories: P-glycoprotein substrates, Cytochrome P-450 SubstratesEndothelin-1 receptor
go.drugbank.com/bio_entities/BE0000521TargetHumansMediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of binding affinities for ET-A is: ET1 > ET2 >> ET3
Synonyms: ET-A, Endothelin receptor type AHIV-1 retropepsin
go.drugbank.com/bio_entities/BE0004854TargetHuman immunodeficiency virus 1Synonyms: Pepsin ALevodopa
go.drugbank.com/drugs/DB01235ApprovedInvestigationalThe first developed drug product that was approved by the FDA was a levodopa and carbidopa combined product called Sinemet that was approved on May 2, 1975[A177781,L6133]. … Levodopa can be metabolised to dopamine on either side of the blood-brain barrier and so it is generally administered with a dopa decarboxylase inhibitor like carbidopa to prevent metabolism until after
Mixtures: STALEVO® 100/25/200MG TABLETAS RECUBIERTAS CON PELICULA, STALEVO ® 150MG/37.5MG/200MG TABLETAS RECUBIERTAS CON PELICULACategories: levodopa, decarboxylase inhibitor and COMT inhibitorAspartate aminotransferase
go.drugbank.com/bio_entities/BE0001217TargetEscherichia coli (strain K12)Synonyms: Transaminase AFlavodoxin 1
go.drugbank.com/bio_entities/BE0003038TargetEscherichia coli (strain K12)Low-potential electron donor to a number of redox enzymes (Potential). Involved in the reactivation of inactive cob(II)alamin in methionine synthase.
Synonyms: Flavodoxin ACell division protein ZipA
go.drugbank.com/bio_entities/BE0004000TargetEscherichia coli (strain K12)Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring (PubMed:11847116, PubMed:22164258, PubMed:22304478
Synonyms: FtsZ interacting protein ADe Novo Triacylglycerol Biosynthesis TG(a-21:0/a-13:0/i-12:0)
smpdb.ca/view/SMP0038259MetabolicA triglyceride (TG, triacylglycerol, TAG, or triacylglyceride) is an ester derived from glycerol and three fatty acids. … Last, the enzyme diacylglycerol O-acyltransferase synthesizes triacylglycerol from diacylglycerol and a fatty acyl-CoA.
De Novo Triacylglycerol Biosynthesis TG(a-21:0/a-13:0/i-20:0)
smpdb.ca/view/SMP0038266MetabolicA triglyceride (TG, triacylglycerol, TAG, or triacylglyceride) is an ester derived from glycerol and three fatty acids. … Last, the enzyme diacylglycerol O-acyltransferase synthesizes triacylglycerol from diacylglycerol and a fatty acyl-CoA.
De Novo Triacylglycerol Biosynthesis TG(a-21:0/a-15:0/i-13:0)
smpdb.ca/view/SMP0038288MetabolicA triglyceride (TG, triacylglycerol, TAG, or triacylglyceride) is an ester derived from glycerol and three fatty acids. … Last, the enzyme diacylglycerol O-acyltransferase synthesizes triacylglycerol from diacylglycerol and a fatty acyl-CoA.