Cell division protein ZipA

BE0004000ProteinEscherichia coli (strain K12)zipA

Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring (PubMed:11847116, PubMed:22164258, PubMed:22304478, PubMed:23233671, PubMed:9008158). It is acted on by 4 drugs in DrugBank.

Gene name
zipA
UniProtKB entry
P77173Swiss-Prot
Cellular location
Cell inner membrane
Residues / weight
328 residues · 36,475 Da
Also known as
FtsZ interacting protein A

Resolves to

Protein
UniProtP77173UniProt nameZIPA_ECOLI
Gene
NCBI Gene946869GenBank1816522
Pharmacology
KEGGecj:JW2404
Structure
PDB1F46PDB1F47PDB1F7W
Drugs

What you can answer from here — as of September 07, 2019

4DrugsApproved to experimental, with action, bond type and pharmacological action
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5GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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23+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Cell division protein ZipA, and which indications are they being tested in?

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