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Displaying results 711 - 720 of 8696 in total
  1. Drug

    Etoposide

    go.drugbank.com/drugs/DB00773
    ApprovedInvestigational

    A semisynthetic derivative of podophyllotoxin that exhibits antitumor activity. Etoposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. This complex induces breaks in double stranded DNA and prevents repair b...

    Categories: P-glycoprotein inhibitors, P-glycoprotein substratesProducts: MYLAN ETOPOSIDE CONCENTRATE FOR SOLUTION FOR INJECTION 20MG/ML, ETOPOSIDE CONCENTRATE FOR SOLUTION FOR INJECTION 20mg/ml
  2. Drug

    Povidone

    go.drugbank.com/drugs/DB11061
    ApprovedInvestigationalWithdrawn

    It is also used in many technical applications with various roles as an adhesive, additive, and emulsifier. … The FDA withdrew its approval for the use of all intravenous drug products containing povidone.[L43942] Other formulations of povidone continue to be available.

    Mixtures: Visine for Red Eye Cool, Murine Tears for Dry EyesProducts: iVizia Lubricant Eye for Severe Night Dry Eyes
  3. Drug

    Leflunomide

    go.drugbank.com/drugs/DB01097
    ApprovedInvestigational

    Leflunomide was approved by FDA and in many other countries (e.g., Canada, Europe) in 1999.

    Synonyms: alpha,alpha,alpha-Trifluoro-5-methyl-4-isoxazolecarboxy-p-toluidideCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Substrates
  4. Drug

    Alprostadil

    go.drugbank.com/drugs/DB00770
    ApprovedInvestigational

    In 1996, the FDA approved the use of alprostadil, administered either with an intracavernosal injection or an intraurethral suppository, for the treatment of erectile dysfunction, and it is used in men … [A257068,A257088] Alprostadil is also used in neonatal patients with congenital heart defects that depend on a patent ductus for survival until corrective or palliative surgery can be performed.

    Categories: Prostaglandin Receptor AgonistsProducts: CAVERJECT POWDER FOR INJECTION 10 mcg/ml, CAVERJECT POWDER FOR INJECTION 20 mcg/ml
  5. Drug

    RTL-1000

    go.drugbank.com/drugs/DB17946
    Investigational

    RTL-1000 is a recombinant T-Cell receptor ligand being investigated for the treatment of multiple sclerosis.

    Synonyms: Recombinant t-cell receptor ligand rtl-1000, Rtl-1000 (recombinant t-cell receptor ligand)
  6. Drug

    Antithrombin III human

    go.drugbank.com/drugs/DB11598
    ApprovedInvestigational

    A plasma alpha 2 glycoprotein that accounts for the major antithrombin activity of normal plasma and also inhibits several other enzymes. It is a member of the serpin superfamily.

    Products: Anbinex Powder For Injection 500 I.U., Anbinex Powder For Injection 1000 I.U.
  7. Drug

    Japanese encephalitis virus strain sa 14-14-2 antigen (formaldehyde inactivated)

    go.drugbank.com/drugs/DB10769
    ApprovedInvestigational

    Products: IXIARO Suspension for Injection 0.5ml in pre-filled syringe
  8. Drug

    Letrozole

    go.drugbank.com/drugs/DB01006
    ApprovedInvestigational

    Letrozole, or CGS 20267, is an oral non-steroidal type II aromatase inhibitor first described in the literature in 1990.

    Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesProducts: Mar-letrozole, Van-letrozole
  9. Drug

    Brolucizumab

    go.drugbank.com/drugs/DB14864
    ApprovedInvestigational

    Brolucizumab, also known as RTH258 or ESBA1008, is a monoclonal antibody indicated to treat neovascular age related macular degeneration. Brolucizumab was granted FDA approval in October 2019.

    Products: Pagenax 120mg/ml Solution For Injection
  10. Drug

    Lonicera confusa flower

    go.drugbank.com/drugs/DB14344
    Investigational

    It is not an approved drug.

    Synonyms: Shan Yin Hua, Jin Yin Hua (Lonicera Confusa)