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Nadolol
go.drugbank.com/drugs/DB01203ApprovedInvestigational[A34177] Nadolol was granted FDA approval on 10 December 1979.[L7922]
Chymopapain
go.drugbank.com/drugs/DB06752ApprovedWithdrawn[A32688] Chymopapain was developed by Chart Medcl and FDA approved on November 10, 1982. It is currently discontinued.[L2487]
Sulopenem etzadroxil
go.drugbank.com/drugs/DB16335ApprovedInvestigational[L51768] Sulopenem etzadroxil was approved by the FDA in October 2024 for the treatment of uncomplicated urinary tract infections.
Cortisone acetate
go.drugbank.com/drugs/DB01380ApprovedInvestigational[A226300,L13203] Cortisone acetate was granted FDA approval on 13 June 1950.[L15107]
Myristic acid
go.drugbank.com/drugs/DB08231InvestigationalMixtures: Jayjun Real Water Shining Vita Cleansing Foa M, Jayjun Real Water Brightening Black Mask Step 01 Real Water Cleansing Foa MAnifrolumab
go.drugbank.com/drugs/DB11976ApprovedInvestigational[A237044] Anifrolumab was granted FDA approval on 30 July 2021.[L34929] … monoclonal antibodies (anifrolumab, [rontalizumab], and [sifalimumab]) that target the type 1 interferon pathway entered clinical trials as potential treatments for systemic lupus erythematosus, but so far
Gemeprost
go.drugbank.com/drugs/DB08964ApprovedWithdrawnIt is not FDA-approved but available in Japan marketed as Preglandin.
Arimoclomol
go.drugbank.com/drugs/DB05025Approved[L51384] Arimoclomol was approved by the FDA on September 20, 2024, making it the first treatment for Niemann-Pick disease, type C (NPC).
BNT162B2 Omicron (LP.8.1)
go.drugbank.com/drugs/DB23337Approved[L53723] The 2025-2026 formulation of Pfizer-BioNTech's Comirnaty was approved by the US FDA in August 2025.[L53728]
Aliskiren
go.drugbank.com/drugs/DB09026ApprovedInvestigational[A203624] It was developed by Speedel and Novartis and initially approved by the FDA in early 2007.