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Sonidegib
go.drugbank.com/drugs/DB09143ApprovedInvestigationalSonidegib is a Hedgehog signaling pathway inhibitor (via smoothened antagonism) developed as an anticancer agent by Novartis. It was FDA approved in 2015 for the treatment of basal cell carcinoma.
Categories: Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 SubstratesSynonyms: N-[6-(cis-2,6-dimethylmorpholin-4-yl)pyridin-3-yl]-2-methyl-4'-(trifluoromethoxy)[1,1'-biphenyl]-3-carboxamideTrypan blue free acid
go.drugbank.com/drugs/DB09158ApprovedTrypan blue is a diazo dye used in ophthalmic cataract surgery to stain the anterior capsule in the presence of a mature cataract.
Categories: Compounds used in a research, industrial, or household settingViloxazine
go.drugbank.com/drugs/DB09185ApprovedInvestigationalWithdrawnViloxazine is a selective norepinephrine reuptake inhibitor.[L41685] For decades, an immediate-release formulation of viloxazine has been used in Europe as an antidepressant.
Categories: MATE 1 Inhibitors, Cytochrome P-450 SubstratesSynonyms: 2-((2-Ethoxyphenoxy)methyl)morpholineLubazodone
go.drugbank.com/drugs/DB09196ExperimentalIt acts as a serotonin reuptake inhibitor and 5-HT2A receptor antagonist. … Lubazodone (YM-992, YM-35,995) is an arylpiperazine antidepressant which was being developed as a treatment for depression and obsessive compulsive disorder, and reached phase II clinical trials, but was
Categories: Heterocyclic Compounds, 1-RingMoxisylyte
go.drugbank.com/drugs/DB09205ApprovedMoxisylyte, denominated as thymoxamine in the UK, is a specific and orally active α1-adrenergic antagonist.
Synonyms: (2-(4-ACETOXY-2-ISOPROPYL-5-METHYLPHENOXY)ETHYL)DIMETHYLAMINE, 6-ACETOXYTHYMOL 2-(DIMETHYLAMINO)ETHYL ETHERTrimazosin
go.drugbank.com/drugs/DB09206ExperimentalTrimazosin is a sympatholytic alpha blocker.
Categories: Peripheral alpha-1 blockers, Heterocyclic Compounds, 1-RingLoxoprofen
go.drugbank.com/drugs/DB09212ApprovedInvestigationalLoxoprofen is a propionic acid derivative non-steroidal anti-inflammatory drug. … A transdermal preparation was approved for use in Japan in January 2006.
Categories: Non COX-2 selective NSAIDSProducts: LAROVEN %1 TOPÄ°KAL JEL, 50 GRAMBrilaroxazine
go.drugbank.com/drugs/DB09226InvestigationalBrilaroxazine (RP5063) is an investigational atypical antipsychotic which is under development by Reviva Pharmaceuticals for the treatment of schizophrenia and schizoaffective disorder. Reviva Pharmaceuticals also intends to investigate ...
Synonyms: 6-(4-(4-(2,3-Dichlorophenyl)-piperazin-1-yl)-butoxy)-2H-benzo(b)(1,4)oxazin-3(4H)-oneCategories: Serotonin 5-HT2 Receptor Antagonists, Serotonin 5-HT2C Receptor AntagonistsMethylene blue
go.drugbank.com/drugs/DB09241ApprovedInvestigationalMethylene blue is an oxidation-reduction agent. The intravenous form of methylene blue is approved by the FDA for the treatment of pediatric and adult patients with acquired methemoglobinemia. Historically, it has been widely used in Afr...
Mixtures: Urin D/S, Uretron D/SCategories: MATE 1 Inhibitors, MATE 2 InhibitorsUbidecarenone
go.drugbank.com/drugs/DB09270ApprovedInvestigationalNutraceutical[A7874] It is a powerful antioxidant, a lipid-soluble and essential cofactor in mitochondrial oxidative phosphorylation. … [L1062] Ubidecarenone is sold as a dietary supplement and is not FDA approved as a drug - it is not meant to treat, cure or prevent any disease.
Mixtures: Kordel"s CoQ10 75MG + Omega 3-6 Capsules, Q 10 Suprabio +L-CarnitineCategories: P-glycoprotein substrates