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Ozagrel
go.drugbank.com/drugs/DB12017InvestigationalOzagrel has been used in trials studying the treatment of Dry Eye Syndromes.
Categories: Thromboxane-A Synthase, antagonists & inhibitorsEvatanepag
go.drugbank.com/drugs/DB12022InvestigationalEvatanepag has been used in trials studying the treatment of Tibial Fractures.
Categories: Heterocyclic Compounds, 1-RingSarecycline
go.drugbank.com/drugs/DB12035ApprovedInvestigationals Seysara (sarecylcine) as a new first in class narrow spectrum tetracycline derived oral antibiotic for the treatment of inflammatory lesions of non-nodular moderate to severe acne vulgaris in patients … Subsequently, while a number of first line tetracycline therapies like doxycycline and minocycline do exist for treating acne vulgaris, sarecycline presents a new and innovative therapy choice because
Categories: P-glycoprotein inhibitorsCrenigacestat
go.drugbank.com/drugs/DB12050InvestigationalCrenigacestat has been used in trials studying the treatment and basic science of LYMPHOMA, Neoplasms, Solid Tumor, COLON CANCER, and BREAST CANCER, among others.
Categories: Heterocyclic Compounds, 2-RingPardoprunox
go.drugbank.com/drugs/DB12061InvestigationalPardoprunox is a partial dopamine D2 agonist and noradrenergic agonist with serotonin 5-HT1A agonist properties.
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingVolasertib
go.drugbank.com/drugs/DB12062InvestigationalVolasertib has been used in trials studying the treatment of Leukemia, Neoplasms, Leukemia, Myeloid, Acute, Myelodysplastic Syndromes, and Leukemia, Monocytic, Acute, among others.
Categories: Heterocyclic Compounds, 2-RingVabicaserin
go.drugbank.com/drugs/DB12071InvestigationalVabicaserin has been used in trials studying the health services research and treatment of Schizophrenia.
Categories: Serotonin 5-HT2 Receptor Agonists, Serotonin 5-HT2C Receptor AgonistsIberdomide
go.drugbank.com/drugs/DB12101Investigational[L64055] Iberdomide has shown anti-tumor activity in multiple myeloma cells resistant to lenalidomide and pomalidomide, and as a CELMoD is designed to degrade Ikaros and Aiolos more potently than immunomodulatory … accelerated approval on August 13, 2026, in combination with daratumumab and hyaluronidase-fihj and dexamethasone for adults with multiple myeloma who have received at least one prior line of therapy including a
Synonyms: (S)-3-(4-((4-(Morpholinomethyl)benzyl)oxy)-1-oxoisoindolin-2-yl)piperidine-2,6-dione, 2,6-Piperidinedione, 3-(1,3-dihydro-4-((4-(4-morpholinylmethyl)phenyl)methoxy)-1-oxo-2H-isoindol-2-yl)-, (3S)-Categories: Cytochrome P-450 Substrates, P-glycoprotein substratesSultamicillin
go.drugbank.com/drugs/DB12127ApprovedWithdrawnSultamicillin has been used in trials studying the prevention and treatment of Ventilator Associated Pneumonia and Chronic Obstructive Pulmonary Disease (COPD).
Categories: Penicillin G, Heterocyclic Compounds, 2-RingProducts: BACTESUL 1 G/ 5 ML, BACMICINE® 250 MG / 5 MLDilmapimod
go.drugbank.com/drugs/DB12140InvestigationalDilmapimod (SB-681323) is a p38 MAP-kinase inhibitor that has potential uses in inflammatory conditions such as RA (Rheumatoid Arthritis).
Categories: Heterocyclic Compounds, 1-Ring