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Oxyphenbutazone
go.drugbank.com/drugs/DB03585ApprovedWithdrawnOxyphenbutazone was withdrawn from the Canadian market in March 1985 due to concerns regarding bone marrow suppression.
Metralindole
go.drugbank.com/drugs/DB09306ExperimentalMetralindole, also known as Inkazan, is similar in structure and pharmacology to pirlindole. It functions as a reversible inhibitor of monoamine oxidase A. … In Russia, this drug was investigated for potential antidepressant activity.
2-(1-(1-(2-chlorophenyl)-2-methoxy-2-oxoethyl)-4-sulfanyl-3-piperidinylidene) acetic acid
go.drugbank.com/drugs/DB19221Investigational2-(1-(1-(2-chlorophenyl)-2-methoxy-2-oxoethyl)-4-sulfanyl-3-piperidinylidene) acetic acid is under investigation in clinical trial NCT03774394 (Impact of Chronic Kidney Disease on Clopidogrel Effects in
Melogliptin
go.drugbank.com/drugs/DB20789ExperimentalMelogliptin is a small molecule drug. The usage of the INN stem '-gliptin' in the name indicates that Melogliptin is a dipeptidyl aminopeptidase-IV inhibitor.
Garvagliptin
go.drugbank.com/drugs/DB21280ExperimentalGarvagliptin is a small molecule drug. The usage of the INN stem '-gliptin' in the name indicates that Garvagliptin is a dipeptidyl aminopeptidase-IV inhibitor.
Acellular nerve allograft
go.drugbank.com/drugs/DB30293ApprovedInvestigationalOur team is working on the full update, which will be available soon. [L54673,L54668] … Approved by the FDA under a Biologics License Application (BLA) as an acellular nerve scaffold for the treatment of adult and pediatric patients (aged ≥1 month) with sensory, mixed, and motor peripheral
ABX1100
go.drugbank.com/drugs/DB17655InvestigationalABX1100 is an investigational Centyrin-siRNA conjugate that targets the Gys1 gene, which encodes glycogen synthase 1 (Gys1), an enzyme that is responsible for glycogen synthesis in the muscle. … It was first developed by Aro Biotherapeutics and is being investigated for the treatment of Pompe disease.[L45978]
Plosaracetam
go.drugbank.com/drugs/DB21594InvestigationalPlosaracetam is a small molecule drug. The usage of the INN stem '-racetam' in the name indicates that Plosaracetam is a piracetam type amide type nootrope agent. … Plosaracetam is under investigation in clinical trial NCT05199142 (A Study to Evaluate the Safety, Tolerability, and Pharmacodynamics of SDI-118 in Elderly Male and Female Study Participants With Cognitive
Istisociclib
go.drugbank.com/drugs/DB21703InvestigationalIstisociclib is a small molecule drug. The usage of the INN stem '-ciclib' in the name indicates that Istisociclib is a cyclin dependant kinase inhibitor. … Istisociclib is under investigation in clinical trial NCT04718675 (A Study of KB-0742 in Participants With Relapsed or Refractory Solid Tumors Including Platinum Resistant High Grade Serous Ovarian Cancer
Atirmociclib
go.drugbank.com/drugs/DB21733InvestigationalAtirmociclib is a small molecule drug. The usage of the INN stem '-ciclib' in the name indicates that Atirmociclib is a cyclin dependant kinase inhibitor. … Atirmociclib is under investigation in clinical trial NCT06760637 (Study of PF-07220060 With Letrozole in Adults With HR-positive HER2-negative Breast Cancer Who Have Not Received Anticancer Treatment