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Tenoxicam
go.drugbank.com/drugs/DB00469ApprovedInvestigationalTenoxicam, an antiinflammatory agent with analgesic and antipyretic properties, is used to treat osteoarthritis and control acute pain.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 SubstratesProducts: TILCOTIL 20 MG 10 SUPP, TENOKTIL 20 MG KAPSÜL, 10 ADETBrimonidine
go.drugbank.com/drugs/DB00484ApprovedInvestigational[A178945] Thus brimonidine is an effective and safe alternative to beta-blockers, in patients with, or at high risk for, cardiopulmonary disease. … [A178951] It is considered to be a third generation alpha-2 aadrenergic receptor agonist, since it displays preferential binding at alpha-2 adrenoceptors over alpha-1 receptors.
Mixtures: SIMBRINZA EYE DROPS, SUSPENSION 10 MG/ML + 2 MG/ML, SİMBRİNZA 10 MG/ML + 2 MG/ML GÖZ DAMLASI, SÜSPANSİYON, 5 MLCategories: Sympathomimetics Used as DecongestantsGlimepiride
go.drugbank.com/drugs/DB00222ApprovedInvestigationalCompared to [glipizide], another second SU drug, glimepiride has a longer duration of action. … It is sometimes classified as a third-generation SU because it has larger substitutions than other second-generation SUs.
Mixtures: METGLITAL LEX 850 MG / 2 MG TABLETAS DE LIBERACION PROLONGADA, METGLITAL LEX 850 MG / 2 MG TABLETAS DE LIBERACION PROLONGADACategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 SubstratesPantothenic acid
go.drugbank.com/drugs/DB01783ApprovedInvestigationalNutraceuticalVet approvedOnly the dextrorotatory (D) isomer of pantothenic acid possesses biological activity. while the levorotatory (L) form may antagonize the effects of the dextrorotatory isomer. … For many animals, pantothenic acid is an essential nutrient as it is required to synthesize coenzyme-A (CoA), as well as to synthesize and metabolize proteins, carbohydrates, and fats.
Mixtures: Iron 25mg With Vit B-cmplx, Vit C, Cu & Mo, B Plus C 300 mgSynonyms: D-pantothenic acidFinasteride
go.drugbank.com/drugs/DB01216ApprovedInvestigationalIt works in a similar fashion as [dutasteride], which is another 5-alpha-reductase inhibitor, by exerting antiandrogenic effects. … Finasteride is a synthetic 4-azasteroid compound [L10565] and specific inhibitor of steroid Type II 5α-reductase, which is an intracellular enzyme that converts the androgen testosterone into 5α-dihydrotestosterone
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: PROSTERIT 5 MG FILM TABLET, 100 ADET, DILAPROST 5 MG FILM KAPLI TABLET, 100 ADETEntecavir
go.drugbank.com/drugs/DB00442ApprovedInvestigationalEntecavir is an oral antiviral drug used in the treatment of hepatitis B infection. It is marketed under the trade name Baraclude (BMS). … Entecavir is a guanine analogue that inhibits all three steps in the viral replication process, and the manufacturer claims that it is more efficacious than previous agents used to treat hepatitis B (lamivudine
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesProducts: VORIX® 1.0 MG, ENTECAVIR AL 1MGMivacurium
go.drugbank.com/drugs/DB01226ApprovedWithdrawnMivacurium is a bisbenzylisoquinolinium based neuromuscular blocker or muscle relaxant. … It binds competitively to cholinergic receptors on the motor end-plate to antagonize the action of acetylcholine, resulting in a block of neuromuscular transmission.
Products: MIVACRON INJECTION 10 mg/5 ml, MİVACRON 10 MG/5 ML ENJEKSİYONLUK ÇÖZELTİ, 5 ADETRiluzole
go.drugbank.com/drugs/DB00740ApprovedInvestigationalA glutamate antagonist (receptors, glutamate) used as an anticonvulsant (anticonvulsants) and to prolong the survival of patients with amyotrophic lateral sclerosis. … Riluzole is marketed as Rilutek by Sanofi.
Categories: Compounds used in a research, industrial, or household setting, Cytochrome P-450 SubstratesProducts: RILUZOL AL 50MG, RILUZOL AL 50MG FTALorlatinib
go.drugbank.com/drugs/DB12130ApprovedInvestigationalinclude lorlatinib as a first-line treatment option in advanced ALK-positive NSCLC. … Lorlatinib is a third-generation ALK tyrosine kinase inhibitor (TKI) for patients with ALK-positive metastatic non-small cell lung cancer[L39905] which was first approved by the US FDA in November of 2018
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 InducersProducts: LORBRENA® 100 MG, LORVIQUA (TABLETS 100 MG)Hydrotalcite
go.drugbank.com/drugs/DB13322ApprovedInvestigationalWithdrawnProducts: JASIVENTER 500 MG, ALKA - SELTZER RA REGULADOR DE ACIDEZ - SUSPENSION