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Ketotifen
go.drugbank.com/drugs/DB00920ApprovedInvestigational[A231204] In the US, it is now used in an over-the-counter ophthalmic formulation for the treatment of itchy eyes associated with allergies,[L32278] and in Canada a prescription-only oral formulation is … available and indicated as an add-on therapy for children with atopic asthma.
Categories: Antihistamines for Systemic UseProducts: Zaditen konservierungsmittelfrei 0,025% - Augentropfen in Einzeldosisbehältnissen, Nu-ketotifen Syrup - 1mg/5mlFlupentixol
go.drugbank.com/drugs/DB00875ApprovedInvestigationalWithdrawnIt is approved for use in Canada and other countries around the world, but not in the US. … It is used for the management of chronic schizophrenia in patients whose main manifestations do not include excitement, agitation or hyperactivity.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeProducts: Fluanxol Depot Inj 20mg/ml, Fluanxol Depot Inj 100mg/mlTrimebutine
go.drugbank.com/drugs/DB09089ApprovedInvestigationalIt is used to restore normal bowel function and is commonly present in pharmaceutical mixtures as trimebutine maleate salt form. … Trimebutine is not a FDA-approved drug, but it is available in Canada and several other international countries.
Categories: Drugs for Functional Gastrointestinal DisordersInternational brands: Ni Wei Fu, Puridat FortCilastatin
go.drugbank.com/drugs/DB01597ApprovedInvestigationalCilastatin is an inhibitor of renal dehydropeptidase, an enzyme responsible for both the metabolism of thienamycin beta-lactam antibiotics as well as conversion of leukotriene D4 to leukotriene E4. … Since the antibiotic, [imipenem], is one such antibiotic that is hydrolyzed by dehydropeptidase, cilastatin is used in combination with imipenem to prevent its metabolism.
Mixtures: BACQURE FOR IV INJECTION 500MG, PREPENEM FOR IV INJECTION 500MGSynonyms: (Z)-7-((R)-2-Amino-2-carboxy-ethylsulfanyl)-2-[((S)-2,2-dimethyl-cyclopropanecarbonyl)-amino]-hept-2-enoic acidZinc sulfate
go.drugbank.com/drugs/DB09322ApprovedInvestigationalIt is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system. … Zinc sulfate is the inorganic compound with the formula ZnSO4 and historically known as "white vitriol".
Mixtures: Tricare Prenatal DHA One Rx Multivitamin, Rohto All-In-OneCategories: Agents for Treatment of Hemorrhoids and Anal Fissures for Topical UseIvermectin
go.drugbank.com/drugs/DB00602ApprovedInvestigationalVet approved[L36763,A238929] In addition, the use of aggregate patient data in large-scale meta-analyses (as opposed to individual patient data (IPD)) has been shown to disguise otherwise blatant data errors, such … While studies are still ongoing, much of the evidence for ivermectin in COVID-19 relies on pre-print _in vitro_ data, and the clinical utility of this data remains unclear.
Mixtures: Heartgard Plus Chewable Tablet for Dogs - Up to 25 lbs, Eqvalan Duo Oral Paste for HorseCategories: Compounds used in a research, industrial, or household settingAtezolizumab
go.drugbank.com/drugs/DB11595ApprovedInvestigational[A18493,L7489] This medication is reserved for patients whose tumors express PD-L1, cannot receive platinum-based chemotherapy, or whose tumors do not respond to platinum-based chemotherapy. … [L7489] In November 2022, the manufacturer (Genentech) voluntarily withdrew the use of atezolizumab for the treatment of urothelial carcinoma, previously approved under the FDA's Accelerated Approval Program
Products: TECENTRIQ CONCENTRATE FOR SOLUTION FOR INFUSION 840MG/14ML, Tecentriq 60mg/ml Concentrate for Solution for InfusionTemsirolimus
go.drugbank.com/drugs/DB06287ApprovedInvestigationalTemsirolimus was approved by the FDA in late May 2007 as well as the European Medicines Agency (EMEA) on November 2007. … Temsirolimus is a derivative of sirolimus used in the treatment of renal cell carcinoma (RCC). It was developed by Wyeth Pharmaceuticals under the trade name Torisel.
Products: Torisel Concentrate for Injection 25mg/mL, TORISEL 25 MG/ML IV INFUZYONLUK COZELTI ICEREN FLAKON, 1 ADETTheophylline
go.drugbank.com/drugs/DB00277ApprovedInvestigationalTheophylline is marketed under several brand names such as Uniphyl and Theochron, and it is indicated mainly for asthma, bronchospasm, and COPD.
Mixtures: Theophylline in Dextrose, Theophylline in DextroseCategories: Drugs for Obstructive Airway DiseasesHuman C1-esterase inhibitor
go.drugbank.com/drugs/DB06404ApprovedInvestigationalThe disease is characterized by acute attacks of painful, and in some cases, fatal swelling of several soft tissues or edema, which may last up to five days when untreated.[L16586, L16606] … [L16586, L16606] This drug is indicated for prophylaxis and treatment of Hereditary Angioedema (HAE), a human genetic disorder caused by a shortage of C1 inhibitor activity that results in an overreaction
Categories: Drugs Used in Hereditary AngioedemaSynonyms: C1-INH