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Ustekinumab
go.drugbank.com/drugs/DB05679ApprovedInvestigational[A187349] It was generated via recombinant human IL-12 immunization of human Ig (hu-Ig) transgenic mice. … Ustekinumab is a human immunoglobulin (Ig) G1 kappa monoclonal antibody directed against interleukin(IL)-12 and IL-23, which are cytokines that are involved in immune and inflammatory responses.
Products: STELARA 130 MG, STELARA® 90 MG/MLThiotepa
go.drugbank.com/drugs/DB04572ApprovedInvestigationalN,N'N'-triethylenethiophosphoramide (ThioTEPA) is a cancer chemotherapeutic member of the alkylating agent group, now in use for over 50 years. … It is also used as conditioning for Bone marrow transplantation. Its main toxicity is myelosuppression.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 InhibitorsProducts: TEPADINA 100 mg powder for concentrate for solution for infusion, TEPADINA® 100 MG POLVO PARA CONCENTRADO PARA SOLUCIÓN PARA PERFUSIÓNLanthanum carbonate
go.drugbank.com/drugs/DB06792ApprovedLanthanum carbonate is a phosphate binder marketed under the trade name Fosrenol by Shire Pharmaceuticals. It is a large pill that requires thorough chewing to avoid choking and other gastrointestinal adverse effects. It is used to treat...
Products: ANTAX 1000 MG ORAL TOZ IÇEREN SAŞE ,30 SAŞE, ANTAX 1000 MG ORAL TOZ IÇEREN SAŞE ,90 SAŞETamoxifen
go.drugbank.com/drugs/DB00675ApprovedInvestigational[A1026] Tamoxifen was granted FDA approval on 30 December 1977.[L7799] … Tamoxifen is a non-steroidal antiestrogen used to treat estrogen receptor positive breast cancers as well as prevent the incidence of breast cancer in high risk populations.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A1 SubstratesProducts: TAMOXIT 10 MG FİLM KAPLI TABLET (TAMOFEN), 100 TABLET, NOVOFEN (10 MG)Ranolazine
go.drugbank.com/drugs/DB00243ApprovedInvestigationalIt was originally approved by the FDA in 2006.[L5440]
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 InhibitorsProducts: RAZİNA 1000 MG UZATILMIŞ SALIMLI TABLET, 60 ADET, Rande 500 mg RetardtablettenPoractant alfa
go.drugbank.com/drugs/DB09113ApprovedInvestigationalPoractant alfa is a pulmonary surfactant marketed as Curosurf in the United States and Canada.
Products: CUROSURF 120 MG/1,5 ML INTRATRAKEAL SUSPANSIYON IÇEREN FLAKON, 1 ADET, Curosurf 120 mg - Suspension zur endotracheopulmonalen InstillationMelphalan
go.drugbank.com/drugs/DB01042ApprovedInvestigational[L40928] It was first synthesized in the early 1950s by substituting L-phenylalanine for the methyl group on nitrogen mustard.
Synonyms: 3-(p-(Bis(2-chloroethyl)amino)phenyl)-L-alanine, 4-(Bis(2-chloroethyl)amino)-L-phenylalanineProducts: ALKERAN FOR INJECTION 50 mg/vial, Melphalan medac 50 mg Pulver und Lösungsmittel zur Herstellung einer Injektions-/InfusionslösungApixaban
go.drugbank.com/drugs/DB06605ApprovedInvestigationalApixaban was approved by the FDA on December 28, 2012[L6043]. … Apixaban is an oral, direct, and highly selective factor Xa (FXa) inhibitor of both free and bound FXa, as well as prothrombinase, independent of antithrombin III for the prevention and treatment of thromboembolic
Mixtures: ELIQUIS 30-Day Starter Pack, ELIQUIS 30-Day Starter PackCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesEthionamide
go.drugbank.com/drugs/DB00609ApprovedInvestigationalWithdrawnA second-line antitubercular agent that inhibits mycolic acid synthesis. It also may be used for treatment of leprosy. (From Smith and Reynard, Textbook of Pharmacology, 1992, p868)
Products: ETYOMİD 250 MG DRAJE, 500 ADET, ETYOMID 250 MG DRAJE, 50 ADETDiacerein
go.drugbank.com/drugs/DB11994ApprovedInvestigationalWithdrawnDiacerein is a prodrug which is metabolized to rhein. It is currently approved in France for the treatment of osteoarthritis although the use of diacerein is restricted due to the side effects including severe diarrhea . Diacerein is und...
Categories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 CYP2C9 InhibitorsProducts: Artrolyt 50 mg Kapseln, Verboril 50 mg Kapseln