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Displaying results 7331 - 7340 of 10000 in total
  1. Target

    Angiopoietin-1

    go.drugbank.com/bio_entities/BE0010681
    TargetHumans

    Plays an important role in the regulation of angiogenesis, endothelial cell survival, proliferation, migration, adhesion and cell spreading, reorganization of the actin cytoskeleton, but also maintenance … Implicated in endothelial developmental processes later and distinct from that of VEGF.

    Synonyms: ANG-1
  2. Drug

    Dimenoxadol

    go.drugbank.com/drugs/DB01461
    ExperimentalIllicit

    Dimenoxadol is an opioid analgesic which produces typical opioid effects such as analgesia and sedation. It is structurally similar to methadone and is a benzilic acid derivative. … In the United States it is classified as a Schedule I controlled drug.

  3. Drug

    MT-0169

    go.drugbank.com/drugs/DB17430
    Investigational

    MT-0169 is a usion protein comprised of an enzymatically active Shiga-like toxin-I A1 subunit fused to a human single chain variable fragment with affinity for human CD38 cell surface protein.

  4. Drug

    Fenticonazole

    go.drugbank.com/drugs/DB13434
    Investigational

    Fenticonazole has a broad spectrum of antimycotic activity against dermatophytes and yeasts.[A275048]

    Categories: Imidazole and Triazole Derivatives, Genito Urinary System and Sex HormonesProducts: Lomexin 600mg - Vaginalkapsel
  5. Drug

    Pimicotinib

    go.drugbank.com/drugs/DB18972
    Investigational

    It was initially developed by Abbisko Therapeutics Co in collaboration with Merck KGaA. [L53748] Pimicotinib was granted Fast Track Designation in December 2023 by the FDA. [L53753] … Pimicotinib is under investigation in clinical trial NCT05804045 (Study of Pimicotinib (ABSK021) for Tenosynovial Giant Cell Tumor (MANEUVER)).

    Synonyms: 1-Pyrrolidinecarboxamide, 3,3-dimethyl-N-[6-methyl-5-[[2-(1-methyl-1H-pyrazol-4-yl)-4-pyridinyl]oxy]-2-pyridinyl]-2-oxo-, 3,3-Dimethyl-N-[6-methyl-5-[[2-(1-methyl-1H-pyrazol-4-yl)-4-pyridinyl]oxy]-2-pyridinyl]-2-oxo-1-pyrrolidinecarboxamide
  6. Indication

    Invasive Meningococcal Infection caused by Neisseria meningitidis serogroup Y

    go.drugbank.com/conditions/DBCOND0093729
    Drugs: Meningococcal (groups A, C, Y and W-135) oligosaccharide diphtheria CRM197 conjugate vaccine · Meningococcal polysaccharide vaccine group Y · Neisseria meningitidis group A capsular polysaccharide tetanus toxoid conjugate antigen · Neisseria meningitidis group y capsular polysaccharide diphtheria toxoid conjugate antigen
  7. Drug

    Bamipine

    go.drugbank.com/drugs/DB13489
    Investigational

    Bamipine is a first-generation antihistamine.

  8. Drug

    Darapladib

    go.drugbank.com/drugs/DB06311
    Investigational

  9. Drug

    Levilimab

    go.drugbank.com/drugs/DB16387
    Investigational

    Levilimab is under investigation in clinical trial NCT04227366 (Study of the Efficacy and Safety of BCD-089 in Combination With Methotrexate in Patients With Active Rheumatoid Arthritis).

    Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating Agents
  10. Indication

    Corneal injuries

    go.drugbank.com/conditions/DBCOND0026236
    Drugs: Prednisolone
    Synonyms: CA - Corneal abrasion