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Displaying results 7331 - 7340 of 10000 in total
  1. Drug

    Serabelisib

    go.drugbank.com/drugs/DB14935
    Investigational

    of TAK-117 (MLN1117) in Healthy Participants). … Serabelisib is under investigation in clinical trial NCT02625259 (A Study to Evaluate the Relative Bioavailability, Effect of Food, and Gastric Potential Hydrogen (pH) Modification on the Pharmacokinetics

  2. Drug

    Siagoside

    go.drugbank.com/drugs/DB12351
    Investigational

    It is a naturally occurring substance in the nerve cell’s membrane that is thought to play a role in cell growth, development, and repair. … Treatment results in a 52% decrease in mortality 48 hours after the induction of ischemia in gerbils by permanent unilateral ligation of the common carotid artery.

  3. Drug

    TT-232

    go.drugbank.com/drugs/DB12088
    Investigational

    Tln 232 is under investigation in clinical trial NCT00422786 (Phase II Study of CAP-232 in Patients With Refractory Metastatic Renal Cell Carcinoma).

  4. Drug

    Basroparib

    go.drugbank.com/drugs/DB21582
    Investigational

    Basroparib is under investigation in clinical trial NCT04505839 (First-In-Human Dose-Escalation Study of STP1002 in Patients With Advanced-Stage Solid Tumors). … Basroparib is a small molecule drug. The usage of the INN stem '-parib' in the name indicates that Basroparib is a poly-ADP-Ribose polymerase inhibitor.

  5. Drug

    Phosphoaminophosphonic Acid-Adenylate Ester

    go.drugbank.com/drugs/DB04395
    Experimental

    An analog of ATP, in which the oxygen atom bridging the beta to the gamma phosphate is replaced by a nitrogen atom. … It is a potent competitive inhibitor of soluble and membrane-bound mitochondrial ATPase and also inhibits ATP-dependent reactions of oxidative phosphorylation. [PubChem]

  6. Drug

    AAV9/MFSD8

    go.drugbank.com/drugs/DB18616
    Experimental

    AAV9/MFSD8 is a gene therapy developed by Neurogene Inc. … It is an adeno-associated virus serotype 9 (AAV9) vector with an engineered transgene encoding the human CLN7/MFSD8 gene for expression of active human major facilitator superfamily domain containing 8

    Synonyms: An adeno-associated virus serotype 9 (AAV9) vector with engineered transgene encoding the human CLN7/MFSD8 gene for expression of active human major facilitator superfamily domain containing 8
  7. Drug

    Salanersen

    go.drugbank.com/drugs/DB18418
    Investigational

    BIIB115 is an investigational antisense oligonucleotide in development for spinal muscular atrophy.

  8. Drug

    Ceftibuten

    go.drugbank.com/drugs/DB01415
    ApprovedInvestigational

    Ceftibuten is a third-generation cephalosporin antibiotic that is orally-administered. … It is typically used to treat acute bacterial exacerbations of chronic bronchitis (ABECB), acute bacterial otitis media, pharyngitis, and tonsilitis.

  9. Drug

    Cabiotraxetan

    go.drugbank.com/drugs/DB20465
    Experimental

    Cabiotraxetan is a small molecule drug. The usage of the INN stem '-xetan' in the name indicates that Cabiotraxetan is a chelating agent.

  10. Drug

    Cligosiban

    go.drugbank.com/drugs/DB20573
    Experimental

    Cligosiban is a small molecule drug. The usage of the INN stem '-siban' in the name indicates that Cligosiban is a oxytocin antagonist. Cligosiban has a monoisotopic molecular weight of 419.12 Da.