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Upacicalcet
go.drugbank.com/drugs/DB20023InvestigationalUpacicalcet is under investigation in clinical trial NCT05836220 (Parathyroid Hormone (PTH) Attenuation Trial in Hemodialysis-2). Upacicalcet has a monoisotopic molecular weight of 351.03 Da. … The usage of the INN stem '-calcet/-calcet-' in the name indicates that Upacicalcet is a calcium-sensing receptor (CaSR) agonist.
Atuveciclib
go.drugbank.com/drugs/DB20084InvestigationalAtuveciclib is under investigation in clinical trial NCT02345382 (Phase I Dose Escalation of BAY1143572 in Subjects With Acute Leukemia). Atuveciclib has a monoisotopic molecular weight of 387.12 Da. … The usage of the INN stem '-ciclib' in the name indicates that Atuveciclib is a cyclin dependant kinase inhibitor.
Bavtavirine
go.drugbank.com/drugs/DB21527InvestigationalBavtavirine is under investigation in clinical trial NCT05585307 (Study of Novel Antiretrovirals in Participants With HIV-1). Bavtavirine has a monoisotopic molecular weight of 416.17 Da. … The usage of the INN stem '-virine' in the name indicates that Bavtavirine is a non-nucleoside reverse transcriptase inhibitor (NNRTI).
Basroparib
go.drugbank.com/drugs/DB21582InvestigationalBasroparib is under investigation in clinical trial NCT04505839 (First-In-Human Dose-Escalation Study of STP1002 in Patients With Advanced-Stage Solid Tumors). … The usage of the INN stem '-parib' in the name indicates that Basroparib is a poly-ADP-Ribose polymerase inhibitor.
Amdizalisib
go.drugbank.com/drugs/DB21514InvestigationalAmdizalisib is under investigation in clinical trial NCT05713110 (A Study of Tazemetostat in Combination With HMPL-689 in Patients With Relapsed/Refractory Lymphoma).
Reparixin
go.drugbank.com/drugs/DB12614Investigational1, and Pancreatic Islet Transplantation in Type 1 Diabetes Mellitus. … Reparixin has been used in trials studying the treatment and prevention of Breast Cancer, Metastatic Breast Cancer, Pancreatectomy for Chronic Pancreatitis, Islet Transplantation in Diabetes Mellitus Type
β-Hydroxythiofentanyl
go.drugbank.com/drugs/DB09170ExperimentalIllicitβ-Hydroxythiofentanyl is an analgesic of the _opioid_ class. This drug is an analog of fentanyl, a potent opioid.
Pegapamodutide
go.drugbank.com/drugs/DB14817InvestigationalPegapamodutide is under investigation in clinical trial NCT02188303 (A Study of LY2944876 in Healthy Japanese and Non-Japanese Participants).
Icrucumab
go.drugbank.com/drugs/DB14824InvestigationalIcrucumab is under investigation in clinical trial NCT01111604 (A Study of IMC-1121B or IMC-18F1 in Colorectal Cancer).
PF-5190457
go.drugbank.com/drugs/DB14870InvestigationalPF-5190457 is under investigation in clinical trial NCT01522807 (A Study Of Three PF-05190457 Formulations In Healthy Volunteers).