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Camptothecin
go.drugbank.com/drugs/DB04690InvestigationalCamptothecin is an alkaloid isolated from the stem wood of the Chinese tree, <i>Camptotheca acuminata</i>. This compound selectively inhibits the nuclear enzyme DNA topoisomerase, type I.
Categories: Topoisomerase I InhibitorsFerumoxsil
go.drugbank.com/drugs/DB09507ApprovedWithdrawnCategories: Compounds used in a research, industrial, or household settingNB-001
go.drugbank.com/drugs/DB12716InvestigationalNB-001 has been investigated for the treatment of Recurrent Herpes Labialis.
Categories: Nucleic Acids, Nucleotides, and NucleosidesCovid-19 Coronavirus Artificial Antigen Presenting Cell Vaccine
go.drugbank.com/drugs/DB15813InvestigationalSpecifically, the COVID-19 infection relies on the binding of the Spike protein to an ACEII receptor, and with the described approach, the vaccine uses these engineered minigenes to express viral proteins … As of August 2020, this vaccine is being tested for prophylaxis against COVID-19 in human clinical trials.
Autologous Hematopoietic Peripheral Blood Stem Cells
go.drugbank.com/drugs/DB17067InvestigationalAutologous hematopoietic peripheral blood stem cells were tested in a clinical trial (NCT00424489) by Northwestern University for the treatment of refractory myasthenia gravis.
REC-994
go.drugbank.com/drugs/DB15616InvestigationalREC-994 was cleared by the FDA in July, 2018 for a phase I trial for the treatment of cerebral cavernous malformation (CCM).
Recombinant human kallikrein-1
go.drugbank.com/drugs/DB19232InvestigationalRecombinant human kallikrein-1 is under investigation in clinical trial NCT01845064 (A Study to Evaluate the Safety and Effectiveness of DM199 in Healthy Subjects and Type 2 Diabetes Patients).
Categories: Enzymes and Coenzymes, Amino Acids, Peptides, and ProteinsNeutramycin
go.drugbank.com/drugs/DB20809ExperimentalNeutramycin is a small molecule drug. The usage of the INN stem '-mycin' in the name indicates that Neutramycin is a antibiotic, produced by Streptomyces strain.
Rutamycin
go.drugbank.com/drugs/DB19908ExperimentalRutamycin is a small molecule drug. The usage of the INN stem '-mycin' in the name indicates that Rutamycin is a antibiotic, produced by Streptomyces strain.
Heliomycin
go.drugbank.com/drugs/DB20233ExperimentalHeliomycin is a small molecule drug. The usage of the INN stem '-mycin' in the name indicates that Heliomycin is a antibiotic, produced by Streptomyces strain.