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Displaying results 7361 - 7370 of 10000 in total
  1. Drug

    RAPA-501-Allo

    go.drugbank.com/drugs/DB15890
    Investigational

    RAPA-501-ALLO is composed of T-cells extracted from healthy volunteers; these cells are then reprogrammed _ex vivo_ in a process that involves de-differentiation and re-differentiation.[L16483]

  2. Drug

    Lutetium Lu177 Edotreotide

    go.drugbank.com/drugs/DB17278
    Investigational

    Categories: Compounds used in a research, industrial, or household setting, Indicators and Reagents
  3. Drug

    Isoluminol

    go.drugbank.com/drugs/DB02041
    Experimental

    Categories: Indicators and Reagents, Compounds used in a research, industrial, or household setting
  4. Target

    Aminoglycoside nucleotidyltransferase (4')

    go.drugbank.com/bio_entities/BE0003547
    EnzymeStaphylococcus aureus

    Inactivates the antibiotic kanamycin by catalyzing the transfer of a nucleotidyl group from nucleoside triphosphates such as ATP to the 4'-hydroxyl group of the aminoglycoside.

    Synonyms: ANT(4')
  5. Target

    Angiopoietin-related protein 3

    go.drugbank.com/bio_entities/BE0010034
    TargetHumans

    Can bind to adipocytes to activate lipolysis, releasing free fatty acids and glycerol (PubMed:12565906). … ; the function does not require ANGPTL3 proteolytic cleavage but seems to be mediated by the N-terminal domain, and is not inhibited by GPIHBP1 (PubMed:12097324, PubMed:19318355, PubMed:20581395).

    Synonyms: ANG-5
  6. Drug

    OTL-201

    go.drugbank.com/drugs/DB17652
    Experimental

    OTL-201 is an investigational hematopoietic stem cell (HSC) gene therapy being developed by Orchard Therapeutics for the treatment of mucopolysaccharidosis type IIIA (MPS-IIIA). … It consists of a lentiviral vector to insert a functional copy of the human N-Sulfoglucosamine Sulfohydrolase (SGSH) gene into autologous CD34+ hematopoietic stem cells.[L45973]

  7. Drug

    Avexitide

    go.drugbank.com/drugs/DB14806
    ApprovedInvestigationalWithdrawn

    Avexitide is under investigation in clinical trial NCT02996812 (Evaluation of Single Ascending Doses of Subcutaneous Exendin 9-39 in Patients With Post-Bariatric Hypoglycemia).

    Categories: Amino Acids, Peptides, and Proteins
  8. Drug

    1-(3-bromophenyl)-7-chloro-6-methoxy-3,4-dihydroisoquinoline

    go.drugbank.com/drugs/DB08555
    Experimental

    These are aromatic polycyclic compounds containing an isoquinoline moiety, which consists of a benzene ring fused to a pyridine ring and forming benzo[c]pyridine. … 1-(3-bromophenyl)-7-chloro-6-methoxy-3,4-dihydroisoquinoline is a solid. This compound belongs to the isoquinolines and derivatives.

  9. Drug

    Trefoil Factor 2

    go.drugbank.com/drugs/DB15750
    Experimental

    The trefoil factor 2 (TFF2) peptide is a low-molecular weight protein and one of the three trefoil-motif-containing proteins. … The peptides themselves are most abundant in mucous cells of the gastric mucosa with TFF2 being detected in mucous layers over the tissue.

  10. Drug

    Cotadutide

    go.drugbank.com/drugs/DB15194
    Investigational

    Cotadutide is under investigation in clinical trial NCT03444584 (Study of MEDI0382 in Combination With Dapagliflozin and Metformin in Overweight/Obese Subject With Type 2 Diabetes).

    Categories: Amino Acids, Peptides, and Proteins