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Telratolimod
go.drugbank.com/drugs/DB19590InvestigationalTelratolimod is a small molecule drug. The usage of the INN stem '-tolimod' in the name indicates that Telratolimod is a toll-like receptor (TLR) agonist. … Telratolimod is under investigation in clinical trial NCT06680479 (Safety and Immunogenicity of Stabilized CH505 TF chTrimer Vaccination in Adults Living With HIV-1 on Suppressive Antiretroviral Therapy
Icenticaftor
go.drugbank.com/drugs/DB21466InvestigationalIcenticaftor is a small molecule drug. … Icenticaftor is under investigation in clinical trial NCT04396366 (Study of Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of QBW251 in Subjects With Bronchiectasis).
Tuxobertinib
go.drugbank.com/drugs/DB21508InvestigationalTuxobertinib is a small molecule drug. The usage of the INN stem '-ertinib' in the name indicates that Tuxobertinib is a epidermal growth factor receptor (EGFR) inhibitor. … Tuxobertinib is under investigation in clinical trial NCT04209465 (A Study of BDTX-189, an Orally Available Allosteric ErbB Inhibitor, in Patients With Advanced Solid Tumors.).
Linvencorvir
go.drugbank.com/drugs/DB21544InvestigationalLinvencorvir is a small molecule drug. The usage of the INN stem '-corvir' in the name indicates that Linvencorvir is a core protein (Cp) inhibitor. … Linvencorvir is under investigation in clinical trial NCT04225715 (A Trial To Evaluate The Efficacy And Safety Of Multiple Combination Therapies In Participants With Chronic Hepatitis B).
Fipravirimat
go.drugbank.com/drugs/DB21578InvestigationalFipravirimat is a small molecule drug. The usage of the INN stem '-virimat' in the name indicates that Fipravirimat is a antiviral, disruptor of viral maturation. … Fipravirimat is under investigation in clinical trial NCT04493216 (A Dose-Range Finding Clinical Trial Study in Human Immunodeficiency Virus (HIV-1) Infected Treatment-Naive Adults).
Foselutoclax
go.drugbank.com/drugs/DB21663InvestigationalFoselutoclax is a small molecule drug. The usage of the INN stem '-toclax' in the name indicates that Foselutoclax is a B-cell lymphoma 2 (Bcl-2) inhibitor. … Foselutoclax is under investigation in clinical trial NCT06011798 (Assess the Efficacy and Safety of Repeat Intravitreal Injections of Foselutoclax (UBX1325) in Patients With DME (ASPIRE)).
NBQ72S
go.drugbank.com/drugs/DB26052InvestigationalNBQ72S is a small molecule drug. NBQ72S is under investigation in clinical trial NCT06810804 (A Phase IIa Study to Evaluate NBQ72S).
Pralurbactam
go.drugbank.com/drugs/DB19437InvestigationalPralurbactam is under investigation in clinical trial NCT06633718 (Study to Assess the Efficacy and Safety of Meropenem and Pralurbactam in CIAI).
Synonyms: 1R,2S,5R)-2-{[2-(guanidinooxy)ethoxy]carbamoyl}-7-oxo-1,6-diazabicyclo[3.2.1]octan-6-yl hydrogen sulfate, (1R,2S,5R)-2-[[[2-[[(Aminoiminomethyl)amino]oxy]ethoxy]amino]carbonyl]-7-oxo-1,6-diazabicyclo[3.2.1]oct-6-yl hydrogen sulfateRocbrutinib
go.drugbank.com/drugs/DB19445InvestigationalRocbrutinib is under investigation in clinical trial NCT05716087 (A Study of Rocbrutinib in Participants With Relapse or Refractory Mantle Cell Lymphoma).
Synonyms: -2H-pyran-4-yl)-1-piperazinyl]phenyl]-2-propena, -methyl-4-(tetrahydro-2H-pyran-4-yl)-1-piperazinyl]phCodrituzumab
go.drugbank.com/drugs/DB14843InvestigationalCodrituzumab is under investigation in clinical trial NCT01507168 (A Study of RO5137382 (GC33) in Patients With Advanced or Metastatic Hepatocellular Carcinoma).