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Displaying results 7381 - 7390 of 10000 in total
  1. Drug

    Apilimod

    go.drugbank.com/drugs/DB05611
    Investigational

    Categories: Heterocyclic Compounds, 1-Ring
  2. Drug

    Edaxeterkib

    go.drugbank.com/drugs/DB21490
    Investigational

    Edaxeterkib is a small molecule drug. The usage of the INN stem '-terkib' in the name indicates that Edaxeterkib is a extracellular signal-regulated kinase (ERK) inhibitor. … Edaxeterkib is under investigation in clinical trial NCT03051035 (First-in-Human Study of KO-947 in Non-Hematological Malignancies). Edaxeterkib has a monoisotopic molecular weight of 469.22 Da.

  3. Drug

    L-cysteic acid

    go.drugbank.com/drugs/DB03661
    Experimental

    L-cysteic acid is a beta-sulfoalanine. It is an amino acid with a C-terminal sulfonic acid group which has been isolated from human hair oxidized with permanganate. … It occurs normally in the outer part of the sheep's fleece, where the wool is exposed to light and weather.

    Synonyms: 3-sulfo-L-alanine, 2-Amino-3-sulfopropionic acid
  4. Drug

    Perillyl alcohol

    go.drugbank.com/drugs/DB15289
    Investigational

    Perillyl alcohol is under investigation in clinical trial NCT02704858 (Safety and Efficacy Study in Recurrent Grade IV Glioma).

    Synonyms: (±)-1-CYCLOHEXENE-1-METHANOL, 4-(1-METHYLETHENYL)-, 1-CYCLOHEXENE-1-METHANOL, 4-(1-METHYLETHENYL)-
  5. Drug

    Xylazine

    go.drugbank.com/drugs/DB11477
    InvestigationalVet approved

    Xylazine is a clonidine analog used as a non-opioid tranquilizer in veterinary medicine and as an emetic, especially in cats. … [A32545] Xylazine is not approved for human use and requires a veterinary licence for its purchase and use.

    Categories: Heterocyclic Compounds, 1-Ring, Adrenergic alpha-2 Receptor Agonists
  6. Drug

    Quaternium-18

    go.drugbank.com/drugs/DB11305
    ApprovedWithdrawn

    Acute oral and percutaneous toxicity tests in animals indicate that they exhibit little or no systemic toxic effects. … Quaternium-18 is a mixture of quaternary ammonium chloride salts. Quaternium-18 Hectorite and Bentonite are the reaction products of Quaternium-18 with clays.

  7. Drug

    Ocadusertib

    go.drugbank.com/drugs/DB21732
    Investigational

    Ocadusertib is a small molecule drug. The usage of the INN stem '-sertib' in the name indicates that Ocadusertib is a serine/threonine kinase inhibitor. … Ocadusertib is under investigation in clinical trial NCT05848258 (An Adaptive Phase 2a/2b Study of LY3871801 in Adult Participants With Rheumatoid Arthritis).

  8. Drug

    Tunicamycin

    go.drugbank.com/drugs/DB13172
    Experimental

    Tunicamycin blocks N-linked glycosylation (N-glycans) resulting in cell cycle arrest at the G1 phase in human cells. It is used as an experimental tool to induce unfolded protein response. … One member of this family is the enzyme GlcNAc phosphotransferase (GPT), which catalyzes the transfer of N-acetylglucosamine-1-phosphate from UDP-N-acetylglucosamine to dolichol phosphate in the first

    Categories: Heterocyclic Compounds, 1-Ring
  9. Drug

    (R)-acetoin

    go.drugbank.com/drugs/DB04364
    Experimental

    A product of fermentation. It is a component of the butanediol cycle in microorganisms. In mammals it is oxidized to carbon dioxide.

    Synonyms: (R)-3-hydroxy-2-butanone, (R)-3-hydroxybutan-2-one
  10. Drug

    (S)-acetoin

    go.drugbank.com/drugs/DB02788
    Experimental

    A product of fermentation. It is a component of the butanediol cycle in microorganisms. In mammals it is oxidized to carbon dioxide.

    Synonyms: (S)-2-acetoin, (S)-acetoin