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Deferasirox
go.drugbank.com/drugs/DB01609ApprovedInvestigationalDeferasirox is an iron chelator and the first oral medication FDA approved for chronic iron overload in patients receiving long term blood transfusions.
Categories: Compounds used in a research, industrial, or household setting, Cytochrome P-450 CYP3A InducersProducts: THALADEF 180 MG, Deferasirox STADA 180 mg FilmtablettenSotorasib
go.drugbank.com/drugs/DB15569ApprovedInvestigationalSotorasib, also known as AMG-510, is an acrylamide-derived KRAS inhibitor developed by Amgen. … [L34288] This mutation makes up >50% of all KRAS mutations.[A187550] Mutant KRAS discovered in 1982 but was not considered a druggable target until the mid-2010s.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 InducersProducts: LUMAKRAS 120 MG FİLM KAPLI TABLET, 240 ADETNitrendipine
go.drugbank.com/drugs/DB01054ApprovedWithdrawnNitrendipine is a calcium channel blocker with marked vasodilator action.
Mixtures: Baroprine 10 mg/20 mg Tabletten, Cenipres 10 mg/20 mg TablettenCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesDapsone
go.drugbank.com/drugs/DB00250ApprovedInvestigationalA sulfone active against a wide range of bacteria but mainly employed for its actions against mycobacterium leprae.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 InducersProducts: Dapsone 100 mg, DAPSULON® 100 MGEfavirenz
go.drugbank.com/drugs/DB00625ApprovedInvestigationalEfavirenz (brand names Sustiva® and Stocrin®) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) and is used as part of highly active antiretroviral therapy (HAART) for the treatment of a human … Efavirenz is also used in combination with other antiretroviral agents as part of an expanded postexposure prophylaxis regimen to prevent HIV transmission for those exposed to materials associated with a
Mixtures: FORSTAVIR-LE ( Efavirenz 600 mg, Lamivudine 300 mg and Tenofovir Disoproxil Fumarate 300 mg ) Film-coated Tablets, Symfi LoCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 InducersNaloxone
go.drugbank.com/drugs/DB01183ApprovedInvestigationalVet approved[L33734] Kits commonly include the supplies necessary to treat an overdose in a non-medical setting such as alcohol swabs, syringes, a rescue breathing mask, and instructions for use. … Notably, if injected into a person not currently using opioid medications, there would be no noticeable effects at all.
Mixtures: Targin 30 mg/15 mg Retardtabletten, Targin 15 mg/7,5 mg RetardtablettenCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InhibitorsAtosiban
go.drugbank.com/drugs/DB09059ApprovedInvestigationalAlthough initial studies suggested it could be used as a nasal spray and hence would not require hospital admission, it is not used in that form.
Products: Atosiban EVER Pharma 75 mg/10 ml Konzentrat zur Herstellung einer Infusionslösung, Atosiban Aguettant 6,75 mg/0,9 ml InjektionslösungNebivolol
go.drugbank.com/drugs/DB04861ApprovedInvestigationalNebivolol is a racemic mixture of 2 enantiomers where one is a beta adrenergic antagonist and the other acts as a cardiac stimulant without beta adrenergic activity. … [A182579] Treatment with nebivolol leads to a greater decrease in systolic and diastolic blood pressure than [atenolol], [propranolol], or [pindolol].
Mixtures: AMLONEB 10 MG/10 MG TABLET, 30 ADET, AMLONEB 10 MG/10 MG TABLET, 90 ADETCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesChronic Motor and Vocal Tic Disorder
go.drugbank.com/conditions/DBCOND0082272Synonyms: Gilles de la Tourette, Gilles de La Tourette's DiseaseFructose
go.drugbank.com/drugs/DB04173ApprovedInvestigationalMixtures: Good Neighbor Pharmacy Nausea Relief, Good Neighbor Pharmacy Anti NauseaCategories: Compounds used in a research, industrial, or household setting