Search

Displaying results 7391 - 7400 of 8696 in total
  1. Target

    VLA-4 (very late antigen-4)

    go.drugbank.com/bio_entities/BE0010014
    TargetHumans

    Integrin alpha-3/beta-1 is a receptor for epiligrin, thrombospondin and CSPG4. Alpha-3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration. … It may also participate in cytolytic T-cell interactions with target cells.

    Synonyms: Fibronectin receptor subunit beta
  2. Target

    NACHT, LRR and PYD domains-containing protein 3

    go.drugbank.com/bio_entities/BE0010347
    TargetHumans

    Sensor component of the NLRP3 inflammasome, which mediates inflammasome activation in response to defects in membrane integrity, leading to secretion of inflammatory cytokines IL1B and IL18 and pyroptosis (PubMed:16407889, PubMed:1840367...

    Synonyms: Angiotensin/vasopressin receptor AII/AVP-like
  3. Drug

    JNJ-64400141

    go.drugbank.com/drugs/DB24373
    Investigational

    JNJ-64400141 is under investigation in clinical trial NCT05242432 (A Study of Adenovirus Serotype 26.Respiratory Syncytial Virus.Pre-Fusion F (Ad26.RSV.preF)-Based Vaccine for Prevention of Respiratory

  4. Drug

    Masitinib

    go.drugbank.com/drugs/DB11526
    InvestigationalVet approved

    In the USA it is distributed under the name Kinavet and has been available for veterinaries since 2011.

  5. Drug

    Utatrectinib

    go.drugbank.com/drugs/DB21295
    Investigational

    Utatrectinib is under investigation in clinical trial NCT01468324 (AZD7451 for Recurrent Gliomas). Utatrectinib has a monoisotopic molecular weight of 382.17 Da. … The usage of the INN stem '-trectinib' in the name indicates that Utatrectinib is a tropomyosin receptor kinase (TRK) inhibitor.

  6. Drug

    Talastine

    go.drugbank.com/drugs/DB13349
    Experimental

    Categories: Antihistamines for Systemic Use
  7. Drug

    Nicofetamide

    go.drugbank.com/drugs/DB13531
    Experimental

    Categories: Drugs for Functional Gastrointestinal Disorders
  8. Drug

    Dimethylaminopropionylphenothiazine

    go.drugbank.com/drugs/DB13672
    Experimental

    Categories: Drugs for Functional Gastrointestinal Disorders
  9. Drug

    TBC-3711

    go.drugbank.com/drugs/DB05407
    Investigational

    TBC3711 is a next-generation endothelin antagonist that is being studied through oral and intravenous formulations by Encysive Pharmaceuticals.

    Categories: Endothelin Receptor Antagonists, Endothelin A Receptor Antagonists
  10. Drug

    Influenza A virus A/Washington/19/2020 (H1N1) antigen (MDCK cell derived, propiolactone inactivated)

    go.drugbank.com/drugs/DB16727
    ApprovedWithdrawn

    Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence against future exposure to the virus, or "antigen