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Displaying results 7411 - 7420 of 10000 in total
  1. Drug

    Nedocromil

    go.drugbank.com/drugs/DB00716
    Approved

    A pyranoquinolone derivative that inhibits activation of inflammatory cells which are associated with asthma, including eosinophils, neutrophils, macrophages, mast cells, monocytes, and platelets.

    Synonyms: 9-Ethyl-6,9-dihydro-4,6-dioxo-10-propyl-4H-pyrano(3,2-g)chinolin-2,8-dicarbonsäure, 9-ethyl-6,9-dihydro-4,6-dioxo-10-propyl-4H-pyrano(3,2-g)quinoline-2,8-dicarboxylic acidProducts: Tilade Inhaler 2mg/aem
  2. Drug

    AICA ribonucleotide

    go.drugbank.com/drugs/DB01700
    Investigational

    5-Aminoimidazole-4-carboxamide ribonucleotide (AICAR) is an intermediate in the generation of inosine monophosphate and analog of adenosine monophosphate (AMP) that is capable of stimulating AMP-dependent … The drug was first used in the 1980s as a method to preserve blood flow to the heart during surgery and is currently of interest as a potential treatment for diabetes by increasing the metabolic activity

  3. Drug

    Vudalimab

    go.drugbank.com/drugs/DB18833
    Investigational

    Vudalimab is under investigation in clinical trial NCT05005728 (Xmab®20717 (Vudalimab) Alone or in Combination With Chemotherapy or Targeted Therapy in Patients With Metastatic Castration-resistant Prostate

    Synonyms: Immunoglobulin half-ig g1-kappa/scfv-h-ch2-ch3, anti-(homo sapiens ctla4 (cytotoxic t-lymphocyte-associated protein 4, cd152)) and anti-(homo sapienspdcd1 (programmed cell death 1, pd-1, pd1, cd279)),
  4. Drug

    Iclepertin

    go.drugbank.com/drugs/DB19058
    Investigational

    Iclepertin is under investigation in clinical trial NCT05211947 (A Study to Test Long-term Safety of Iclepertin in People With Schizophrenia Who Took Part in a Previous CONNEX Study).

  5. Drug

    Esaxerenone

    go.drugbank.com/drugs/DB15207
    Investigational

    Esaxerenone is under investigation in clinical trial NCT02722265 (Long-term Study of CS-3150 as Monotherapy or in Combination With Other Antihypertensive Drug in Japanese Patients With Essential Hypertension

  6. Drug

    Balcinrenone

    go.drugbank.com/drugs/DB15418
    Investigational

    AZD-9977 is under investigation in clinical trial NCT03843060 (A Phase 1 Study to Assess the Pharmacokinetics of AZD9977 Administered Alone and in Combination With Itraconazole in Healthy Volunteers).

  7. Drug

    SER-100

    go.drugbank.com/drugs/DB16013
    Investigational

    SER-100 is under investigation in clinical trial NCT01987284 (SER100 in Isolated Systolic Hypertension).

  8. Drug

    Mitazalimab

    go.drugbank.com/drugs/DB15225
    Investigational

    Mitazalimab is under investigation in clinical trial NCT02379741 (ADC-1013 First-in-Human Study).

  9. Drug

    Methcathinone

    go.drugbank.com/drugs/DB15339
    Experimental

    Methcathinone is under investigation in clinical trial NCT02617862 (PCI Imaging System in Pediatric Ophthalmology).

  10. Drug

    Egaptivon pegol

    go.drugbank.com/drugs/DB05202
    Investigational

    Egaptivon pegol, formerly known as ARC1779, is a therapeutic aptamer antagonist of the A1 domain of von Willebrand Factor (vWF), the ligand for receptor glycoprotein 1b on platelets.