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St. John's Wort
go.drugbank.com/drugs/DB01323ApprovedNutraceuticalCategories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeCoenzyme A
go.drugbank.com/drugs/DB01992InvestigationalNutraceuticalAll genomes sequenced to date encode enzymes that use coenzyme A as a substrate, and around 4% of cellular enzymes use it, or a thioester form of it, as a substrate. … It is used as a supplement for the hypothetical treatment of acne.
Categories: Coenzyme A, biosynthesisSynonyms: Coenzyme ANeisseria meningitidis group a capsular polysaccharide diphtheria toxoid conjugate antigen
go.drugbank.com/drugs/DB10798ApprovedInvestigationalNeisseria meningitidis group a capsular polysaccharide diphtheria toxoid conjugate antigen is an active intramuscular immunization for the prophylaxis of invasive meningococcal disease caused by *Neisseria … meningitidis* serogroup a.
Synonyms: Neisseria meningitidis group a capsular polysaccharide diphtheria toxoid conjugate antigen, Neisseria meningitidis serogroup A capsular polysaccharide diphtheria toxoid protein conjugate vaccineDeutarserine
go.drugbank.com/drugs/DB19057InvestigationalDeutarserine is under investigation in clinical trial NCT04158687 (A Phase 2 Study to Evaluate the Safety and Efficacy of CTP-692 as an Adjunctive Treatment in Adults With Schizophrenia).
Synonyms: D-serine-2-dEzatiostat
go.drugbank.com/drugs/DB05460InvestigationalThese are compounds containing an amide derived from two or more amino carboxylic acid molecules (the same or different) by formation of a covalent bond from the carbonyl carbon of one to the nitrogen … It might also be relevant as an adjunct therapy since a reduction in blood cell levels is also a common, toxic effect of many standard chemotherapeutic drugs.
GSK-923295
go.drugbank.com/drugs/DB06097InvestigationalGSK-923295 demonstrated a broad spectrum of activity against a range of human tumor xenografts grown in nude mice, including models of colon, breast, ovarian, lung and other tumors. … GSK-923295 is a small-molecule inhibitor of the mitotic kinesin centromere-associated protein E (CENP-E), and the third novel drug candidate to arise from Cytokinetics' broad strategic alliance with GlaxoSmithKline
humanized SMART Anti-IL-12 Antibody
go.drugbank.com/drugs/DB05848ExperimentalIL-12 is a cytokine that may have considerable potential as a target in the therapy of autoimmune diseases. … The humanized anti-IL-12 antibody is an important addition to PDL's already strong pipeline of humanized antibodies being developed for the treatment of autoimmune diseases.
Palucorcel
go.drugbank.com/drugs/DB17955InvestigationalPalucorcel is an investigational stem cell therapy consisting of human umbilical tissue-derived cells. … Developed by Janssen Biotech, it is being investigated for the treatment of various conditions such as amyotrophic lateral sclerosis (ALS) and macular degeneration.
KB001
go.drugbank.com/drugs/DB05222InvestigationalKB001 is a Humaneered™ PEGylated monoclonal antibody fragment for the treatment of life-threatening Pseudomonas aeruginosa infections, a common problem of cystic fibrosis and mechanically ventilated