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Displaying results 7481 - 7490 of 10000 in total
  1. Target

    Endothelin-1 receptor

    go.drugbank.com/bio_entities/BE0000521
    TargetHumans

    Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of binding affinities for ET-A is: ET1 > ET2 >> ET3

    Synonyms: ET-A, Endothelin receptor type A
  2. Drug

    Repaglinide

    go.drugbank.com/drugs/DB00912
    ApprovedInvestigational

    Approximately one month of therapy is required before a decrease in fasting blood glucose is seen. Meglitnides may have a neutral effect on weight or cause a slight increase in weight. … Approximately 90% of a single orally administered dose is eliminated in feces and 8% in urine.

    Mixtures: REPAMEF 1/1000 MG EFERVESAN TABLET, 30 ADET, REPAMEF 1/500 MG EFERVESAN TABLET, 30 ADETCategories: Drugs Used in Diabetes, Cytochrome P-450 Substrates
  3. Drug

    Acorus calamus root

    go.drugbank.com/drugs/DB14292
    Investigational

    Acorus calamus root is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

    Products: derma MOBALNA EP 90 Hair Again Toner
  4. Drug

    Tamoxifen

    go.drugbank.com/drugs/DB00675
    ApprovedInvestigational

    Tamoxifen is a non-steroidal antiestrogen used to treat estrogen receptor positive breast cancers as well as prevent the incidence of breast cancer in high risk populations. … [A1025,L7799,L7802] Tamoxifen is used alone or as an adjuvant in these treatments.

    Synonyms: (Z)-2-(4-(1,2-Diphenyl-1-butenyl)phenoxy)-N,N-dimethylethanamine, (Z)-2-(para-(1,2-Diphenyl-1-butenyl)phenoxy)-N,N-dimethylamineInternational brands: Nolvadex-D
  5. Target

    HIV-1 retropepsin

    go.drugbank.com/bio_entities/BE0004854
    TargetHuman immunodeficiency virus 1

    Synonyms: Pepsin A
  6. Drug

    Clindamycin

    go.drugbank.com/drugs/DB01190
    ApprovedInvestigationalVet approved

    Clindamycin is a semi-synthetic lincosamide antibiotic used in the treatment of a variety of serious infections due to susceptible microorganisms[L11599,L11596] as well as topically for acne vulgaris. … The name lincomycin is derived from Lincoln, Nebraska, where it was first isolated from _Streptomyces lincolnensis_ found in a soil sample.[A190621]

    Synonyms: Methyl 7-chloro-6,7,8-trideoxy-6-(1-methyl-trans-4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-L-threo-alpha-D-galacto-octopyranoside, 7(S)-Chloro-7-deoxylincomycinInternational brands: Dalacin C, Dalacin T Topical Solution
  7. Target

    Aspartate aminotransferase

    go.drugbank.com/bio_entities/BE0001217
    TargetEscherichia coli (strain K12)

    Synonyms: Transaminase A
  8. Target

    Flavodoxin 1

    go.drugbank.com/bio_entities/BE0003038
    TargetEscherichia coli (strain K12)

    Low-potential electron donor to a number of redox enzymes (Potential). Involved in the reactivation of inactive cob(II)alamin in methionine synthase.

    Synonyms: Flavodoxin A
  9. Target

    Cell division protein ZipA

    go.drugbank.com/bio_entities/BE0004000
    TargetEscherichia coli (strain K12)

    Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring (PubMed:11847116, PubMed:22164258, PubMed:22304478

    Synonyms: FtsZ interacting protein A
  10. Pathway

    De Novo Triacylglycerol Biosynthesis TG(a-21:0/a-13:0/i-12:0)

    smpdb.ca/view/SMP0038259
    Metabolic

    A triglyceride (TG, triacylglycerol, TAG, or triacylglyceride) is an ester derived from glycerol and three fatty acids. … Last, the enzyme diacylglycerol O-acyltransferase synthesizes triacylglycerol from diacylglycerol and a fatty acyl-CoA.

    Drugs: NADH · sn-glycerol 3-phosphate · Dihydroxyacetone phosphate