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Xylometazoline
go.drugbank.com/drugs/DB06694ApprovedXylometazoline works by binding to alpha (α)-adrenergic receptors to cause vasoconstriction of nasal blood vessels. … Xylometazoline is an imidazoline derivative [A228523] with sympathomimetic and nasal decongestant activity.
Categories: Decongestants and AntiallergicsProducts: Cold and Allergy Decongestant Nasal Spray, Otrivin Cold and Allergy Decongestant Nose DropsStyphnolobium japonicum flower bud
go.drugbank.com/drugs/DB14294InvestigationalStyphnolobium japonicum flower bud is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Synonyms: Huai Flower Bud, Huaihua (Flower Bud)Products: BARAMO for O ily Scalp, BARAMO Scalp Serum for O ily ScalpKetamine
go.drugbank.com/drugs/DB01221ApprovedInvestigationalVet approvedIt was FDA approved in 1970, and from there, it has been used as an anesthetic for children or patients undergoing minor surgeries but mainly for veterinary purposes.[L1332] … It started being used for veterinary purposes in Belgium and in 1964 was proven that compared to PCP, it produced minor hallucinogenic effects and shorter psychotomimetic effects.
Categories: Amino Acids, Peptides, and Proteins, N-Methylaspartate, agonistsSynonyms: 2-(o-chlorophenyl)-2-(methylamino)-cyclohexanoneCarboplatin
go.drugbank.com/drugs/DB00958ApprovedInvestigational[A230523] Carboplatin was developed as an analog of [cisplatin] with reduced nephrotoxicity and vomiting.[A230463,A230523] Carboplatin was granted FDA approval on 3 March 1989.[L32248] … Carboplatin is an organoplatinum antineoplastic alkylating agent used in the treatment of advanced ovarian carcinoma.[L32253] Early clinical studies of carboplatin were performed in 1982.
Categories: Indicators and Reagents, Antineoplastic and Immunomodulating AgentsProducts: Neoplatin Inj 10mg/ml, Paraplatin-AQ Inj 10mg/mlSertraline
go.drugbank.com/drugs/DB01104ApprovedInvestigationalSertraline is a popular antidepressant medication commonly known as a selective serotonin reuptake inhibitor (SSRI), and is similar to drugs such as [Citalopram] and [Fluoxetine]. … Sertraline displays enhanced safety or tolerability than other classes of antidepressants, which frequently cause high levels of drowsiness, dizziness, blurred vision, and other undesirable effects.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeSynonyms: (1S-cis)-1,2,3,4-tetrahydro-4-(3,4-dichlorophenyl)-N-methyl-1-naphthalenamineHuman immunoglobulin G
go.drugbank.com/drugs/DB00028ApprovedInvestigationalIVIg is used in the treatment of immunodeficiencies, as well as autoimmune and inflammatory disorders. … IgG subclasses are fully represented in the following proportions: 70.3% IgG1, 24.7% IgG2, 3.1% IgG3, and 1.9% IgG4.
Categories: Amino Acids, Peptides, and ProteinsProducts: PRIVIGEN® 10% (2.5 G/25ML), HIZENTRA® 2G/ 10MLBusulfan
go.drugbank.com/drugs/DB01008ApprovedInvestigationalIt has been used in the palliative treatment of chronic myeloid leukemia (myeloid leukemia, chronic), but although symptomatic relief is provided, no permanent remission is brought about. … Busulfan is a bifunctional alkylating agent, having a selective immunosuppressive effect on bone marrow. It is not a structural analog of the nitrogen mustards.
Categories: Antineoplastic and Immunomodulating AgentsProducts: Myleran Tablets 2mg, MYLOFAN 60MG/ 10ML İ.V. İNFÜZYON İÇİN KONSANTRE ÇÖZELTİ İÇEREN FLAKON, 1 ADETKetorolac
go.drugbank.com/drugs/DB00465ApprovedInvestigationalKetorolac is a Non-steroidal anti-inflammatory drug (NSAID) and is commercially available as an oral tablet, injectable, nasal spray and as an ophthalmic solution. … [L6520] Impressively, ketorolac has a similar efficacy to standard doses of morphine and meperidine making it a useful opioid sparing agent.[L6511]
Categories: Antiinflammatory and Antirheumatic Products, Non-Steroids, Mydriatics and CycloplegicsInternational brands: Dorixina forte NFFenoterol
go.drugbank.com/drugs/DB01288ApprovedWithdrawnFenoterol is an adrenergic beta-2 agonist that is used as a bronchodilator and tocolytic.
Mixtures: PULBRONC NF ADULTOS, BERODUAL N METERED DOSE INHALERCategories: fenoterol and ipratropium bromide, Genito Urinary System and Sex HormonesPhenolphthalein
go.drugbank.com/drugs/DB04824ApprovedWithdrawnPhenolphthalein was withdrawn in Canada due to concerns with carcinogenicity in 1997.
Mixtures: Herbalax Forte No 70 Tab, Lax-BO TabCategories: Indicators and Reagents, Alimentary Tract and Metabolism