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CTX130
go.drugbank.com/drugs/DB18627InvestigationalCTX130 is an allogeneic CRISPR/Cas9-mediated genetically modified CAR T cell therapy targeting CD70 antigen.
Synonyms: Allogeneic CRISPR/Cas9-mediated genetically modified CAR T cells targeting CD70 antigenRizatriptan
go.drugbank.com/drugs/DB00953ApprovedInvestigational[L46018] Used in the treatment of migraines, rizatriptan was first approved in the US in 1998. … Rizatriptan is a second-generation triptan [A258918] and a selective 5-HT<sub>1B and 5-HT1D</sub> receptor agonist.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Heterocyclic Compounds, 1-RingSynonyms: N,N-Dimethyl-2-[5-(1,2,4-triazol-1-ylmethyl)-1H-indol-3-yl]-ethanamine, N,N-Dimethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-1H-indole-3-ethanamineAlprazolam
go.drugbank.com/drugs/DB00404ApprovedIllicitInvestigational[A18125] Alprazolam's adverse effects are generally related to the sedation it can cause. … [L34783, L34788] It is mainly metabolized by CYP3As and so is contraindicated with CYP3A inhibitors like ketoconazole and itraconazole.
Mixtures: NEUPAX DUO-SCategories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 2-RingOriCar-017
go.drugbank.com/drugs/DB17280InvestigationalSynonyms: GPRC5D-CAR-T, chimeric antigen receptor (CAR)-T cell therapy targeting G protein-coupled receptor class-C group-5 member-D (GPRC5D)Mometasone furoate
go.drugbank.com/drugs/DB14512ApprovedInvestigationalVet approvedMometasone furoate is a corticosteroid drug that can be used for the treatment of asthma, rhinitis, and certain skin conditions[FDA Label][F4292,F4295]. … Mometasone furoate is formulated as a dry powder inhaler, nasal spray, and ointment for its different indications[FDA Label][F4292,F4295].
Mixtures: M-FURO FA %0.1 + %2 KREM, 30 G, DERMOTIL-S® UNGUENTOCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersOsteosarcoma Tumor
go.drugbank.com/conditions/DBCOND0066821Synonyms: Osteosarcoma, no ICD-O subtype, Osteosarcoma, no ICD-O subtype (morphologic abnormality)Moclobemide
go.drugbank.com/drugs/DB01171ApprovedInvestigationalA reversible monoamine oxidase inhibitor (MAOI) selective for isoform A (RIMA) used to treat major depressive disorder. … Most meta-analyses and most studies indicate that in the acute management of depression, moclobemide is more efficacious than placebo medication and similarly efficacious as tricyclic antidepressants (
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Cytochrome P-450 SubstratesSynonyms: 4-Chlor-N-(2-morpholinoethyl)benzamid, p-Chloro-N-(2-morpholinoethyl)benzamideRifampin
go.drugbank.com/drugs/DB01045ApprovedInvestigational[A263768] Rifampin is used to treat tuberculosis and works by inhibiting the microbial DNA-dependent RNA polymerase (RNAP).[A263768] … Rifampin, also known as rifampicin, is a broad-spectrum antimicrobial [A263748] that was first discovered in 1965 [A263753] and clinically used in 1968.
Mixtures: RINCURE ® 3 FDC TABLETAS CON PELICULA, DOTBAL-SCategories: P-glycoprotein inducers, Cytochrome P-450 CYP1A2 InducersStage 4 Follicular Lymphoma ( FL)
go.drugbank.com/conditions/DBCOND0154147Drugs: ObinutuzumabSynonyms: Follicle centre lymphoma, follicular grade I, II, III stage IVAtenolol
go.drugbank.com/drugs/DB00335ApprovedInvestigationalAtenolol itself was developed early on in this history by Alvogen Malta under the trade name Tenormin and received FDA approval in September, 1981. … Later they continued to be investigated for use in heart failure throughout the 1970-1980s.
Mixtures: ATENOLOL CO RATIO 100/25MG, PLENACOR DCategories: Cytochrome P-450 Substrates, Adrenergic beta-1 Receptor Antagonists