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Dorzolamide
go.drugbank.com/drugs/DB00869ApprovedInvestigational[A1304] First marketed in 1995,[A190624] dorzolamide is available in ophthalmic solutions as monotherapy marketed as Trusopt [L11377] or in combination with [timolol] as Cosopt PF.[L11380] … [L11377] It works by blocking an enzyme in the ciliary process that regulates ion balance and fluid pressure in the eyes.
Mixtures: Vizidor Duo 20 mg/ml + 5 mg/ml Augentropfen, NEFRIDAXEM B+DCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 SubstratesAsfotase alfa
go.drugbank.com/drugs/DB09105ApprovedInvestigationalHypophosphatasia is almost always fatal when severe skeletal disease is obvious at birth. … Asfotase alfa is a first-in-class bone-targeted enzyme replacement therapy designed to address the underlying cause of hypophosphatasia (HPP)—deficient alkaline phosphatase (ALP).
Products: STRENSİQ 40 MG/1.0 ML ENJEKSİYONLUK ÇÖZELTİ, 12 ADET, STRENSİQ 18 MG/0.45 ML ENJEKSİYONLUK ÇÖZELTİ, 12 ADETVardenafil
go.drugbank.com/drugs/DB00862Approved[A258313] The use of vardenafil as a monotherapy for the treatment of pulmonary arterial hypertension has also been evaluated.[A258308] … Vardenafil is a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5) and an oral therapy for the treatment of erectile dysfunction.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C19 InhibitorsProducts: Vardenafil 1 A Pharma 10 mg - Filmtabletten, Vardenafil 1 A Pharma 5 mg - FilmtablettenStreptococcus pneumoniae type 15A capsular polysaccharide diphtheria CRM197 protein conjugate antigen
go.drugbank.com/drugs/DB19343ApprovedInvestigational_ serotype 15A individually conjugated to the CRM197 protein, a nontoxic variant of diphtheria toxin isolated from cultures of _Corynebacterium diphtheriae_ strain C7 (β197). … Streptococcus pneumoniae type 15A capsular polysaccharide diphtheria CRM197 protein conjugate antigen is a sterile vaccine that contains saccharides of the capsular antigens of _Streptococcus pneumoniae
Synonyms: Streptococcus pneumoniae type 15A capsular polysaccharide diphtheria CRM197 protein conjugate antigenRomosozumab
go.drugbank.com/drugs/DB11866ApprovedInvestigationalRomosozumab is a humanized monoclonal antibody indicated for the treatment of osteoperosis in postmenopausal women at high risk of fracture and patients who have failed in other treatments or are intolerant … In a comparison study of post menopausal women with osteoporosis and a past fracture, romosozumab for 12 months followed by alendronic acid for 12 months was superior to alendronic acid alone for 24 months
Products: EVENITY SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 105 MG/1.17 ML, EVENİTY 105 MG/1,17 ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 2 ADETLiraglutide
go.drugbank.com/drugs/DB06655ApprovedInvestigationalVictoza contains liraglutide, a synthetic analog of human glucagon-like peptide-1(GLP-1) and acts as a GLP-1 receptor agonist. … [A6932] Liraglutide is made by attaching a C-16 fatty acid (palmitic acid) with a glutamic acid spacer on the remaining lysine residue at position 26 of the peptide precursor.
Mixtures: XULTOPHY 100U/ML+3.6MG/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR KALEM, 10 ADET, Xultophy 100/3.6Products: VICTOZA 6 MG/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR KALEM, 10 ADET, SAXENDA® 6 MG/MLArgatroban
go.drugbank.com/drugs/DB00278ApprovedInvestigationalArgatroban is a direct, selective thrombin inhibitor. … Argatroban is a non-heparin anticoagulant shown to both normalize platelet count in patients with HIT and prevent the formation of thrombi.
Categories: Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A5 Substrates with a Narrow Therapeutic IndexProducts: Argatra Multidose 100 mg/ml Konzentrat zur Herstellung einer Infusionslösung, ARGAZEM 250 MG/2,5 ML I.V. İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 1 ADETUrofollitropin
go.drugbank.com/drugs/DB00094ApprovedVet approvedWithdrawnThe alpha subunit is glycosylated at Asn 51 and Asn 78 while the beta subunit is glycosylated at Asn 7 and Asn 24. … Urofollitropin is a urinary-derived follicle-stimulating hormone (FSH) that is extracted and purified from human urine samples.
Mixtures: Fertinorm Hp 150 - Pws Diluent Im ScProducts: FOSTİMON 150 IU ENJEKSİYONLUK LİYOFİLİZE TOZ (10 FLAKON + 10 AMPUL), FOSTİMON 150 IU ENJEKSİYONLUK LİYOFİLİZE TOZRopivacaine
go.drugbank.com/drugs/DB00296ApprovedInvestigationalIt exists as a racemate of its S- and R-enantiomers, although the marketed form is supplied only as the purified S-enantiomer.[L42140] … Ropivacaine is an aminoamide local anesthetic drug marketed by AstraZeneca under the trade name Naropin.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesProducts: Braun 10 mg/ml Injektionslösung, Naropin 10 mg/ml - InjektionslösungLevodropropizine
go.drugbank.com/drugs/DB12472InvestigationalLevodropropizine is under investigation in clinical trial NCT01573663 (A Drug-Drug Interaction Study of Ambroxol and Levodropropizine).
Mixtures: PULMOTUS 30 MG+ 2 MG/5 ML ŞURUP, 150 ML, DROPOLEV ŞURUP ,150 MLProducts: AZINEX 30 MG/5 ML 150 ML SURUP, LAVENIL 30 MG/5 ML 150 ML SURUP