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Mezigdomide
go.drugbank.com/drugs/DB17584InvestigationalMezigdomide is under investigation in clinical trial NCT05372354 (A Study to Evaluate Safety, Drug Levels and Effectiveness of CC-92480 (BMS-986348) in Combination With Other Treatments in Participants
Isoquercetin
go.drugbank.com/drugs/DB12665InvestigationalVTE in Colorectal Cancer, among others. … Isoquercetin has been used in trials studying the treatment of Kidney Cancer, Renal cell carcinoma, Advanced Renal Cell Carcinoma, Thromboembolism of Vein in Pancreatic Cancer, and Thromboembolism of Vein
SD118
go.drugbank.com/drugs/DB05207ExperimentalSD118 was previously under investigation in Japan for a different indication and now, following re-profiling and evaluation in experimental animal models, has demonstrated its potential as a new oral therapy
Simurosertib
go.drugbank.com/drugs/DB16330InvestigationalSimurosertib is under investigation in clinical trial NCT03261947 (A Study to Evaluate the Safety, Tolerability, and Activity of TAK-931 in Participants With Metastatic Pancreatic Cancer, Metastatic Colorectal
BMS-986104
go.drugbank.com/drugs/DB15214Investigationalof BMS-986104 in Healthy Male Subjects). … BMS-986104 is under investigation in clinical trial NCT02211469 (A Randomized, Placebo-Controlled, Double-Blind, Single Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics
Enristomig
go.drugbank.com/drugs/DB29060InvestigationalINBRX-105 is under investigation in clinical trial NCT03809624 (Study of INBRX-105 and INBRX-105 With Pembrolizumab in Patients With Solid Tumors Including Head and Neck Cancer).
PRO-1562
go.drugbank.com/drugs/DB33979ExperimentalPRO-1562 is under investigation in clinical trial NCT07826689 (A Phase 1/2a Study of Oral PRO-1562 in Healthy Subjects and Patients With Relapsing Multiple Sclerosis).
Velusetrag
go.drugbank.com/drugs/DB12702InvestigationalVelusetrag has been used in trials studying the treatment of Gastroparesis and Alzheimer's Disease. … It is a highly selective serotonin receptor agonist effective in patients with chronic constipation. It is being developed by Theravance.
Icenticaftor
go.drugbank.com/drugs/DB21466InvestigationalIcenticaftor is under investigation in clinical trial NCT04396366 (Study of Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of QBW251 in Subjects With Bronchiectasis). … The usage of the INN stem '-caftor' in the name indicates that Icenticaftor is a Cystic fibrosis transmembrane regulator (CFTR) protein modulator, corrector, and amplifier.
Linvencorvir
go.drugbank.com/drugs/DB21544InvestigationalLinvencorvir is under investigation in clinical trial NCT04225715 (A Trial To Evaluate The Efficacy And Safety Of Multiple Combination Therapies In Participants With Chronic Hepatitis B). … The usage of the INN stem '-corvir' in the name indicates that Linvencorvir is a core protein (Cp) inhibitor.