Search

Displaying results 7511 - 7520 of 10000 in total
  1. Drug

    Mirabegron

    go.drugbank.com/drugs/DB08893
    ApprovedInvestigational

    Mirabegron has a comparatively favorable adverse effect profile as compared to other available treatment options, and its complementary mechanism to the antimuscarinics that came before it allows for its … Mirabegron is a sympathomimetic beta-3 adrenergic receptor agonist used to relax the smooth muscle of the bladder in the treatment of urinary frequency and incontinence.

    Categories: P-glycoprotein inhibitors, P-glycoprotein substratesProducts: MYRBETRIC® 50 MG TABLETAS DE LIBERACION PROLONGADA, MYRBETRIC® 25 MG TABLETAS DE LIBERACION PROLONGADA
  2. Drug

    Tofacitinib

    go.drugbank.com/drugs/DB08895
    ApprovedInvestigational

    Tofacitinib is an inhibitor of Janus kinases, a group of intracellular enzymes involved in signalling pathways that affect hematopoiesis and immune cell function.

    Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingProducts: XELJANZ®5MG, เซลแจนซ์ (ยาเม็ด 5 มก.)
  3. Drug

    Ponatinib

    go.drugbank.com/drugs/DB08901
    ApprovedInvestigational

    Ponatinib is a novel Bcr-Abl tyrosine kinase inhibitor that is especially effective against the T315I mutation for the treatment of chronic myeloid leukemia. FDA approved on December 14, 2012.

    Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2C8 Substrates with a Narrow Therapeutic IndexProducts: ICLUSIG® 15 MG TABLETAS RECUBIERTAS
  4. Drug

    Canagliflozin

    go.drugbank.com/drugs/DB08907
    ApprovedInvestigational

    Canagliflozin, also known as _Invokana_, is a sodium-glucose cotransporter 2 (SGLT2) inhibitor used in the management of type 2 diabetes mellitus along with lifestyle changes including diet and exercise … 2 diabetes mellitus [L5897], [FDA label].

    Mixtures: VOKANAMET ® TM_TABLETAS RECUBIERTAS 150/1000 MGCategories: Cytochrome P-450 Substrates, P-glycoprotein inhibitors
  5. Drug

    Iodamide

    go.drugbank.com/drugs/DB08948
    ApprovedWithdrawn

    Iodamide is a contrast medium molecule that is no longer marketed in the United States.

    Categories: X-Ray Contrast Media, Iodinated, Compounds used in a research, industrial, or household setting
  6. Drug

    Hydroxydione

    go.drugbank.com/drugs/DB08956
    ApprovedWithdrawn

    Hydroxydione (Viadril) is a neuroactive steroid used as a general anesthetic.

  7. Drug

    Hexamethonium

    go.drugbank.com/drugs/DB08960
    Experimental

    used a research tool. … A nicotinic cholinergic antagonist often referred to as the prototypical ganglionic blocker. It is poorly absorbed from the gastrointestinal tract and does not cross the blood-brain barrier.

    Synonyms: N,N,N,N',N',N'-hexamethylhexane-1,6-diaminium
  8. Drug

    Dimetotiazine

    go.drugbank.com/drugs/DB08967
    Approved

    Dimetotiazine has considerable antiemetic & serotonin antagonistic action used mainly in allergic skin conditions.

    Categories: Heterocyclic Compounds, 3-Ring
  9. Drug

    Fominoben

    go.drugbank.com/drugs/DB08968
    ApprovedWithdrawn

    Fominoben is an antitussive agent.

    Categories: Heterocyclic Compounds, 1-Ring
  10. Drug

    Etilefrine

    go.drugbank.com/drugs/DB08985
    ApprovedWithdrawn

    Etilefrine is an adrenergic agonist that appears to interact with beta-1 and some alpha-adrenergic receptors. It has been used as a vasoconstrictor agent.

    Categories: Adrenergic beta-1 Receptor Agonists, Compounds used in a research, industrial, or household settingProducts: EFFORTIL® AMPOLLAS, EFFORTIL LOESUNG Z TROPFEN