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Displaying results 7521 - 7530 of 10000 in total

Drug
Pimodivir
go.drugbank.com/drugs/DB14974
Investigational
Pimodivir is under investigation in clinical trial NCT02658825 (A Study to Evaluate the Effect of JNJ-63623872 on Cardiac Repolarization Interval in Healthy Participants).
Categories: Heterocyclic Compounds, 1-Ring
Drug
Desmethylprodine
go.drugbank.com/drugs/DB01478
ExperimentalIllicit
It has been listed as a Schedule I controlled drug in the United States, and thus is not used clinically. It is known to be a designer drug, synthesized in 1977, for the purpose of recreational use. … Desmethylprodine, a derivative of meperidine, is an opioid analgesic with the potency of morphine.
Categories: Cytochrome P-450 CYP2D6 Inhibitors, Heterocyclic Compounds, 1-RingSynonyms: 1-Methyl-4-phenyl-4-piperidinol propionate, 1-Methyl-4-phenyl-4-propionoxypiperidine
Drug
PF-232798
go.drugbank.com/drugs/DB14813
Investigational
PF-232798 is under investigation in clinical trial NCT01140425 (Study To Evaluate The Effect Of A Multiple Oral Dose Of PF-00232798 On QT Intervals In Healthy Subjects).
Categories: Heterocyclic Compounds, 1-Ring
Drug
Human Lactoferrin Peptide hLF1-11
go.drugbank.com/drugs/DB16245
Investigational
Human Lactoferrin Peptide hLF1-11 is under investigation in clinical trial NCT00509834 (A Study on the Tolerability and Early Efficacy of Hlf1-11 in Patients With Proven Candidaemia).
Synonyms: N-terminal peptide of human lactoferrin 1-11, Human lactoferrin 1-11
Drug
Mitiperstat
go.drugbank.com/drugs/DB18963
Investigational
Mitiperstat is under investigation in clinical trial NCT05492877 (An Efficacy and Safety Study of Mitiperstat (AZD4831) (MPO Inhibitor) vs Placebo in the Treatment of Moderate to Severe COPD.).
Synonyms: 1-({2-[(1R)-1-aminoethyl]-4-chlorophenyl}methyl)-2-sulfanylidene-1,2,3,5-tetrahydro-4H-pyrrolo[3,2-d]pyrimidin-4-one, 4H-Pyrrolo[3,2-d]pyrimidin-4-one, 1-[[2-[(1R)-1-aminoethyl]-4-chlorophenyl]methyl]-1,2,3,5-tetrahydro-2-thioxo-Categories: Heterocyclic Compounds, 1-Ring
Drug
Pegmusirudin
go.drugbank.com/drugs/DB19220
Investigational
Pegmusirudin is under investigation in clinical trial NCT00074620 (A Clinical Study to Assess the Safety of Peg-hirudin (SPP200) Compared to Heparin in Patients Who Are on Haemodialysis).
Drug
Viralym-C
go.drugbank.com/drugs/DB17975
Investigational
Viralym-C is an investigational T-cell immunotherapy developed by ViraCyte. It consists of Human Leukocyte Antigen (HLA)-matched cytomegalovirus (CMV)-specific T lymphocytes. … It was granted FDA orphan designation in January 2017 and investigated for the treatment of CMV infection.[A260291, L47241]
Synonyms: Viralym-C
Drug
GC-373
go.drugbank.com/drugs/DB15797
Experimental
Along with its prodrug, GC-376, GC-373 was recently investigated _in vitro_ in cell culture against SARS-Cov-2 Mpro [A219036]. … It is an inhibitor of Mpro (otherwise known as 3CLpro), a viral encoded protease that cleaves and activates functional proteins involved in viral replication and transcription[A219036
Categories: Heterocyclic Compounds, 1-Ring
Drug
Ritobegron
go.drugbank.com/drugs/DB12080
Investigational
Ritobegron is under investigation in clinical trial NCT02256735 (Study to Investigate the Effect of KUC 7483 CL on the QT/QTc Interval of the ECG in Comparison to Placebo and Moxifloxacin in Healthy Male
Categories: Adrenergic beta-3 Receptor Agonists
Drug
Orludodstat
go.drugbank.com/drugs/DB21498
Investigational
Orludodstat is under investigation in clinical trial NCT03404726 (A Study to Investigate BAY2402234, a Dihydroorotate Dehydrogenase (DHODH) Inhibitor, in Myeloid Malignancies). … Orludodstat is a small molecule drug. The usage of the INN stem '-dodstat' in the name indicates that Orludodstat is a dihydro-orotate dehydrogenase (DHODH) inhibitor.
Synonyms: Orludodstat(inn)Categories: Heterocyclic Compounds, 1-Ring