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Nelotanserin
go.drugbank.com/drugs/DB12555InvestigationalIt is a highly selective antagonist at the 5-HT2A serotonin receptor. It increases non-REM sleep, the most restorative phase of the sleep cycle, without sacrificing REM or dream sleep. … Nelotanserin has been used in trials studying the treatment of Lewy Body Dementia, Visual Hallucinations, Dementia With Lewy Bodies, and REM Sleep Behavior Disorder.
Saruparib
go.drugbank.com/drugs/DB18982InvestigationalSaruparib is under investigation in clinical trial NCT06380751 (Saruparib (AZD5305) Plus Camizestrant Compared With CDK4/6 Inhibitor Plus Endocrine Therapy or Plus Camizestrant in Hr-positive, Her2-negative … (IHC 0, 1+, 2+/ ISH Non-amplified), BRCA1, BRCA2, or Palb2m Advanced Breast Cancer).
Synonyms: 2-Pyridinecarboxamide, 5-[4-[(7-ethyl-5,6-dihydro-6-oxo-1,5-naphthyridin-3-yl)methyl]-1-piperazinyl]-N-methyl-, 5-{4-[(7-ethyl-5,6-dihydro-6-oxo-1,5-naphthyridin-3- yl)methyl]piperazin-1-yl}-N-methylpyridine-2- carboxamideMibolerone
go.drugbank.com/drugs/DB11429ExperimentalVet approvedMibolerone is a potent anabolic steroid which is both higher affinity and more selective for the androgen receptor than metribolone.
Synonyms: (7α,17β)-17-hydroxy-7,17-dimethylestr-4-en-3-one, 17-beta-Hydroxy-7-alpha,17-dimethylestr-4-en-3-oneLascufloxacin
go.drugbank.com/drugs/DB20002ExperimentalLascufloxacin is a small molecule drug. The usage of the INN stem '-oxacin' in the name indicates that Lascufloxacin is a nalidixic acid derivative antibacterial.
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UsetgAAVCF
go.drugbank.com/drugs/DB17849InvestigationalIt is being investigated for the treatment of cystic fibrosis.[A259821, A259826] … tgAAVCF is an adeno-associated virus (AAV) vector encoding the human cystic fibrosis transmembrane conductance regulator protein (CFTR) cDNA.
Viralym-C
go.drugbank.com/drugs/DB17975InvestigationalIt was granted FDA orphan designation in January 2017 and investigated for the treatment of CMV infection.[A260291, L47241] … Viralym-C is an investigational T-cell immunotherapy developed by ViraCyte. It consists of Human Leukocyte Antigen (HLA)-matched cytomegalovirus (CMV)-specific T lymphocytes.
Nigella sativa oil
go.drugbank.com/drugs/DB28165InvestigationalNigella Sativa Oil is under investigation in clinical trial NCT06823544 (A Comparative Single Blind Clinical Study on the Effect of Alvogyl, Eugenol, and Nigella Sativa (Black Seed Oil) for Alveolar Osteitis … Nigella Sativa Oil is a biologic drug.
AEM-28-14
go.drugbank.com/drugs/DB17643Experimental[L45909] It is being investigated for lipid disorders such as homozygous familial hypercholesterolemia.[L45914] … AEM-28-14 is an analog of [AEM-28], an apolipoprotein E mimetic peptide, with a 400 percent greater cholesterol-lowering efficacy and a several-fold increase in drug tolerability.
Modimelanotide
go.drugbank.com/drugs/DB15314InvestigationalModimelanotide is under investigation in clinical trial NCT01897519 (A Safety and Efficacy Trial of Multiple Dosing Regimens of ABT-719 for the Prevention of Acute Kidney Injury in Subjects Undergoing
Tiocarlide
go.drugbank.com/drugs/DB13608ExperimentalCategories: Antiinfectives for Systemic Use, Drugs for Treatment of Tuberculosis