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V116517
go.drugbank.com/drugs/DB16060InvestigationalV116517 is under investigation in clinical trial NCT01688947 (Analgesic Efficacy and Safety of V116517 in Subjects With Moderate to Severe Chronic Pain Due to Postherpetic Neuralgia (PHN)).
Categories: Heterocyclic Compounds, 1-RingVincamine
go.drugbank.com/drugs/DB13374InvestigationalVincamine is a monoterpenoid indole alkaloid obtained from the leaves of *Vinca minor* with a vasodilatory property. Studies indicate that vincamine increases the regional cerebral blood flow.
Categories: Heterocyclic Compounds, 2-RingD-Alanine
go.drugbank.com/drugs/DB01786ExperimentalThe D-enantiomer of alanine.
Synonyms: D-α-alanine, (R)-2-aminopropanoic acidIodipamide
go.drugbank.com/drugs/DB04711ApprovedWithdrawnIodipamide is a water-soluble radiographic contrast media for cholecystography and intravenous cholangiography.
Categories: X-Ray Contrast Activity, X-Ray Contrast Media, IodinatedTalactoferrin alfa
go.drugbank.com/drugs/DB05426InvestigationalIt increases body’s immune power and also works as a natural antioxidant, helping to control cell and tissue damage caused by oxidation. … Talactoferrin alfa is a novel immunomodulatory 80 kD protein with demonstrated oral anti-tumor properties. Lactoferrin, a protein found in breast milk is developed by Agennix.
Elbimilast
go.drugbank.com/drugs/DB20663InvestigationalElbimilast is a small molecule drug. The usage of the INN stem '-milast' in the name indicates that Elbimilast is a Phosphodiesterase-4 (PDE4) inhibitor. … Elbimilast is under investigation in clinical trial NCT00977886 (Safety and Pharmacokinetics of ELB353 in Healthy Men). Elbimilast has a monoisotopic molecular weight of 442.04 Da.
AGT-182
go.drugbank.com/drugs/DB17630InvestigationalAGT-182 is an investigational enzyme replacement therapy engineered by the fusion of the iduronate-2-sulfatase (IDS) enzyme and a human insulin receptor monoclonal antibody.
Synonyms: Recombinant human insulin receptor monoclonal antibody-fused iduronate 2-sulfataseD-norleucine
go.drugbank.com/drugs/DB04419ExperimentalAn unnatural amino acid that is used experimentally to study protein structure and function. It is structurally similar to METHIONINE, however it does not contain SULFUR.
Synonyms: D-2-aminohexanoic acid, D-norleucineSphingosine
go.drugbank.com/drugs/DB03203InvestigationalAn amino alcohol with a long unsaturated hydrocarbon chain. Sphingosine and its derivative sphinganine are the major bases of the sphingolipids in mammals. (Dorland, 28th ed)
Categories: P-glycoprotein substratesRegramostim
go.drugbank.com/drugs/DB05386InvestigationalRegramostim (GM-CSF) is a differentially glycosylated factor produced mainly by activated T cells and macrophages. … Endothelial cells and fibroblasts can also produce GM-CSF after exposure to TNF-α, IL-1, IL-2 and IFN-γ. GM-CSF is found associated with extracellular matrix and in membrane-bound formats too.
Synonyms: Colony-stimulating factor 2 (human clone pCSF-1 protein moiety reduced), glycoform GMC 89-107