Elbimilast

DB20663InvestigationalSmall molecule

Elbimilast is a small molecule drug. The usage of the INN stem '-milast' in the name indicates that Elbimilast is a Phosphodiesterase-4 (PDE4) inhibitor. Elbimilast is under investigation in clinical... Elbimilast is under investigation in clinical trial NCT00977886 (Safety and Pharmacokinetics of ELB353 in Healthy Men).

Chemical structure of Elbimilast
Formula / weight
C21H13Cl2FN4O2 · 443.26 g/mol (avg)
Code names
AWD-12353 · ELB-353

Resolves to

Compound
UNIIF49V1L3QBDCAS418794-42-0ChEMBLCHEMBL4568146ChEBI757720PubChem9803446
Structure
InChIKeyJERXUPDBWDWFCF-UHFFFAOYSA-NSMILESFC1=CC=C(CN2C=C(C(=O)C(=O)NC3=C(Cl)C=NC=C3Cl)C3=CC=CN=C23)C=C1
Targets
Q07343PDE4BQ08499PDE4DP27815PDE4A

What you can answer from here — as of September 23, 2026

3Protein targetsEach mapped to UniProt, with action and pharmacological action
Listed above
1Clinical trialPhase, status and sponsor resolved per trial
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3+ReferencesStructured and connected to the statements they support
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Which drugs share a target with Elbimilast, and which of those have an active Phase 3 trial?

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