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Displaying results 7581 - 7590 of 10000 in total
  1. Drug

    Davelizomib

    go.drugbank.com/drugs/DB21660
    Experimental

    Davelizomib is a small molecule drug. The usage of the INN stem '-zomib' in the name indicates that Davelizomib is a proteasome inhibitor. Davelizomib has a monoisotopic molecular weight of 481.18 Da.

  2. Drug

    Foselutoclax

    go.drugbank.com/drugs/DB21663
    Investigational

    Foselutoclax is a small molecule drug. The usage of the INN stem '-toclax' in the name indicates that Foselutoclax is a B-cell lymphoma 2 (Bcl-2) inhibitor. … Foselutoclax has a monoisotopic molecular weight of 1158.28 Da.

  3. Drug

    Sevabertinib

    go.drugbank.com/drugs/DB21667
    ApprovedInvestigational

    [L54638] Sevabertinib functions as a reversible kinase inhibitor of human epidermal growth factor receptor 2 (HER2), also exhibiting activity against epidermal growth factor receptor (EGFR). … Sevabertinib is a kinase inhibitor indicated for adult patients with locally advanced or metastatic non-squamous non-small cell lung cancer (NSCLC) whose tumors have HER2 (ERBB2) tyrosine kinase domain

    Categories: MATE 2-K Inhibitors, MATE 1 Inhibitors
  4. Drug

    Rivasterat

    go.drugbank.com/drugs/DB21668
    Experimental

    Rivasterat is a small molecule drug. Rivasterat has a monoisotopic molecular weight of 626.38 Da.

  5. Drug

    Icovamenib

    go.drugbank.com/drugs/DB21669
    Investigational

    Icovamenib is under investigation in clinical trial NCT06152042 (Phase 2 Trial of BMF-219 in Participants With Type 1 Diabetes Mellitus). Icovamenib has a monoisotopic molecular weight of 566.28 Da. … Icovamenib is a small molecule drug. The usage of the INN stem '-menib' in the name indicates that Icovamenib is a menin interaction inhibitor.

  6. Drug

    Mosperafenib

    go.drugbank.com/drugs/DB21673
    Experimental

    Mosperafenib has a monoisotopic molecular weight of 461.1 Da. … Mosperafenib is a small molecule drug. The usage of the INN stem '-rafenib' in the name indicates that Mosperafenib is a Raf (rapidly accelerated fibrosarcoma) kinase inhibitor.

  7. Drug

    Branosotine

    go.drugbank.com/drugs/DB21674
    Experimental

    Branosotine is a small molecule drug. The usage of the INN stem '-sotine' in the name indicates that Branosotine is a non-peptidic somatostatin receptor agonist. … Branosotine has a monoisotopic molecular weight of 471.22 Da.

  8. Drug

    Ofirnoflast

    go.drugbank.com/drugs/DB21679
    Investigational

    Ofirnoflast is a small molecule drug. The usage of the INN stem '-noflast' in the name indicates that Ofirnoflast is a inflammasome protein NLRP3 inhibitor. … Ofirnoflast has a monoisotopic molecular weight of 501.15 Da.

  9. Drug

    Frevecitinib

    go.drugbank.com/drugs/DB21681
    Investigational

    Frevecitinib is a small molecule drug. The usage of the INN stem '-citinib' in the name indicates that Frevecitinib is a Janus kinase inhibitor. … Frevecitinib has a monoisotopic molecular weight of 415.18 Da.

  10. Drug

    Potrasertib

    go.drugbank.com/drugs/DB21682
    Experimental

    Potrasertib is a small molecule drug. The usage of the INN stem '-sertib' in the name indicates that Potrasertib is a serine/threonine kinase inhibitor. … Potrasertib has a monoisotopic molecular weight of 564.19 Da.