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Displaying results 7581 - 7590 of 10000 in total
  1. Drug

    MYR-101

    go.drugbank.com/drugs/DB17075
    Investigational

    ASPA is produced in oligodendrocytes, and participates in the metabolism of N-acetylaspartate (NAA). … It is caused by a mutation in the aspartoacylase gene (_ASPA_), which leads to a deficiency of the aspartoacylase enzyme (ASPA).

  2. Drug

    Androstenediol

    go.drugbank.com/drugs/DB01524
    ExperimentalIllicit

    Androstenediol is an intermediate in [testosterone] biosynthesis, found in the testis or the adrenal glands. … Androstenediol, derived from dehydroepiandrosterone by the reduction of the 17-keto group (17-hydroxysteroid dehydrogenases), is converted to testosterone by the oxidation of the 3-beta hydroxyl group

  3. Drug

    Osoresnontrine

    go.drugbank.com/drugs/DB16274
    Investigational

    in Patients With Schizophrenia on Stable Antipsychotic Treatment.). … Osoresnontrine is under investigation in clinical trial NCT02281773 (A Study to Investigate the Efficacy, Safety and Tolerability of Four Different Doses of BI 409306 Compared to Placebo Given for 12 Weeks

  4. Drug

    Clocapramine

    go.drugbank.com/drugs/DB09003
    Experimental

    Clocapramine is an atypical antipsychotic of the imidobenzyl class which was introduced in Japan in 1974 for the treatment of schizophrenia. … In addition to psychosis, clocapramine has also been used to augment antidepressants in the treatment of anxiety and panic.

  5. Drug

    Devafidugene civaparvovec

    go.drugbank.com/drugs/DB16790
    Investigational

    Devafidugene civaparvovec is an investigational _in vivo_ genome editing product. … Developed by Sangamo Therapeutics, Inc., devafidugene civaparvovec is being investigated for the treatment of mucopolysaccharidosis Type I (MPS I).[L46716]

  6. Drug

    Carbon black

    go.drugbank.com/drugs/DB11980
    Investigational

    [A263401] Upon inhalation, carbon black has been reported to trigger an inflammatory response in the lung tissue [A263401] and has been linked to carcinogenicity.[A263406, A263411, A263416] … Produced by the incomplete combustion of hydrocarbons, carbon black is an insoluble pigment [A263396] with demonstrated adverse effects on pulmonary function.

    Synonyms: D&C BLACK NO. 2 [II]
  7. Drug

    (3-Carboxy-2-(R)-Hydroxy-Propyl)-Trimethyl-Ammonium

    go.drugbank.com/drugs/DB02648
    Experimental

    It is used therapeutically to stimulate gastric and pancreatic secretions and in the treatment of hyperlipoproteinemias. [PubChem]

  8. Drug

    Trolamine polypeptide oleate condensate

    go.drugbank.com/drugs/DB09373
    ApprovedVet approved

    Various ear diseases and infections are treated with eardrops containing triethanolamine polypeptide oleate-condensate, such as Cerumenex in the United States and Canada.

  9. Drug

    Survodutide

    go.drugbank.com/drugs/DB18989
    Investigational

    Survodutide is under investigation in clinical trial NCT06077864 (A Study to Test the Effect of Survodutide (BI 456906) on Cardiovascular Safety in People With Overweight or Obesity (SYNCHRONIZE™ - CVOT

  10. Drug

    Deoxyribonuclease I

    go.drugbank.com/drugs/DB16523
    Investigational

    Currently, DNase I is being investigated against respiratory failure in COVID-19 in the clinical trial NCT04541979 (Aerosoliserat DNase for Treatment of Respiratory Failure in Severe COVID-19). … Deoxyribonuclease I (DNase I) is a human enzyme responsible for the digestion of extracellular DNA7[A227723]. It is normally found in saliva, urine, pancreatic secretions, and blood[A227723].

    Categories: Deoxyribonuclease I, antagonists & inhibitorsSynonyms: DNase I, Deoxyribonuclease I