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EB05
go.drugbank.com/drugs/DB16477InvestigationalEB05, in combination with standard of care (SOC), is being investigated in clinical trial NCT04401475 to evaluate its safety and efficacy in adult hospitalized patients with COVID-19 and ARDS.
Synonyms: Immunoglobulin G1 [326-serine,329-phenylalanine,de-448-lysine], anti-(human Toll-like receptor 4) (human-Mus musculus monoclonal EB05 γ1-chain), disulfide with human-Mus musculus monoclonal EB05 κ-chainDociparstat sodium
go.drugbank.com/drugs/DB16481InvestigationalSynonyms: 2,3-o-Desulfated heparin (12000 da)SAR443122
go.drugbank.com/drugs/DB16492InvestigationalNCT04469621 was studied in severe COVID-19 patients, while NCT05588843 is currently recruiting participants with ulcerative colitis.
Synonyms: 1H-1,2,4-TRIAZOLE-5-CARBOXAMIDE, 3-(PHENYLMETHYL)-N-((3S)-2,3,4,5-TETRAHYDRO-5-METHYL-4-OXOPYRIDO(3,2-B)(1,4)OXAZEPIN-3-YL)-, 3-(PHENYLMETHYL)-N-((3S)-2,3,4,5-TETRAHYDRO-5-METHYL-4-OXOPYRIDO(3,2-B)(1,4)OXAZEPIN-3-YL)-1H-1,2,4-TRIAZOLE-5-CARBOXAMIDEAcetylcysteine zidrimer
go.drugbank.com/drugs/DB16496InvestigationalSynonyms: Dendrimer N-acetyl-cysteineEnpatoran
go.drugbank.com/drugs/DB16501InvestigationalAdditionally, M5049 was studied for COVID-19 pneumonia in a completed trial with results (NCT04448756) and is currently being recruited for a trial involving participants with dermatomyositis and polymyositis … It was investigated for systemic lupus erythematosus and cutaneous lupus erythematosus in completed trials (NCT04647708 and NCT05162586) and in a recruiting trial (NCT05540327).
Synonyms: 5-((3R,5S)-3-AMINO-5-TRIFLUOROMETHYLPIPERIDIN-1-YL)QUINOLINE-8-CARBONITRILELufotrelvir
go.drugbank.com/drugs/DB16514InvestigationalPF-07304814 is a small molecule prodrug that targets the 3CL<sup>pro</sup> protease (M<sup>pro)</sup>, which is used by viruses like SARS-CoV-2 to assemble and multiply[L31718]. … Now, it is being tested regarding the novel SARS-CoV-2 virus, including studies in conjunction with [Remdesivir] to treat COVID-19 infection; in vitro data showed synergistic effects on articles published
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingInfluenza A virus A/Brisbane/10/2010 live (attenuated) antigen
go.drugbank.com/drugs/DB16517ApprovedA seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed, or inactivated, through exposure to heat or chemicals such as formaldehyde 3.
Synonyms: Influenza A virus A/Brisbane/10/2010 (H1N1) whole, Influenza A virus A/Brisbane/10/2010 (H1N1) wild typeInfluenza A virus A/South Australia/55/2014 live (attenuated) antigen
go.drugbank.com/drugs/DB16518ApprovedA seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed, or inactivated, through exposure to heat or chemicals such as formaldehyde 3.
Synonyms: Influenza A virus A/South Australia/55/2014 (H3N2) whole, Influenza A virus A/South Australia/55/2014 (H3N2) wild typeCollagen-polyvinylpyrrolidone
go.drugbank.com/drugs/DB16525InvestigationalCollagen-polyvinylpyrrolidone is a copolymer generated from a mixture of type I collagen and low-molecular-weight PVP that has undergone γ irradiation[A227733]. … It is characterized by antifibrotic, fibrolytic, and immunomodulatory properties[A227733].
Categories: Heterocyclic Compounds, 1-RingBACTEK-R
go.drugbank.com/drugs/DB16526InvestigationalMV130 contains different components of whole heat-inactivated gram-positive and -negative bacteria that are involved in upper and lower respiratory infections. These include streptococcus pneumoniae and staphylococcus aureus. Though stud...