Identification

Generic Name
Dociparstat sodium
DrugBank Accession Number
DB16481
Background

Not Available

Type
Small Molecule
Groups
Investigational
Synonyms
  • 2,3-o-Desulfated heparin (12000 da)
  • Dociparstat sodium
External IDs
  • GM-1892

Pharmacology

Indication

Not Available

Reduce drug development failure rates
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Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action

Dociparstat sodium is derived from heparin which, like heparin, alters the activities of the CXCL12/CXCR4 axis and inhibits the interactions of proteins including P-selectin, high mobility group box 1, Platelet Factor 4, and human leukocyte elastase.

Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Categories

Drug Categories
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
4O75889WF4
CAS number
177021-00-0
InChI Key
Not Available
InChI
Not Available
IUPAC Name
Not Available
SMILES
Not Available

References

General References
  1. External Link [Link]
  2. External Link [Link]
Not Available

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
3Active Not RecruitingTreatmentAcute Myeloid Leukemia1
2TerminatedTreatmentPancreatic Metastatic Cancer1
2, 3TerminatedTreatmentCoronavirus Disease 2019 (COVID‑19) / Lung Injury, Acute (ALI) / Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
Not Available
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available

Drug created at January 21, 2021 01:47 / Updated at January 18, 2023 15:38