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Methylsamidorphan
go.drugbank.com/drugs/DB15241InvestigationalMethylsamidorphan is under investigation in clinical trial NCT01418092 (ALK37-007: Evaluation of Safety and Efficacy of ALKS 37 (RDC-1036) in Adults With Opioid-induced Constipation (OIC)).
Salvianolic acid A
go.drugbank.com/drugs/DB15246InvestigationalSalvianolic acid A is under investigation in clinical trial NCT03908242 (Phase I Study of Continuous Administration of Salvianolic Acid A Tablet).
Synonyms: Salvianolic acid AVorolanib
go.drugbank.com/drugs/DB15247InvestigationalVorolanib is under investigation in clinical trial NCT03904719 (CM082 and JS001 in Patients With Advanced Small-cell Lung Cancer (SCLC)).
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingMK-6325
go.drugbank.com/drugs/DB15249InvestigationalMK-6325 is under investigation in clinical trial NCT01329913 (Safety, Pharmacokinetics, and Pharmacodynamics of MK-6325 in Hepatitis C Virus (HCV) Infections (MK-6325-003)).
Nemolizumab
go.drugbank.com/drugs/DB15252ApprovedInvestigationalNemolizumab is a humanized monoclonal modified immunoglobulin 2 (IgG2) antibody directed against interleukin-31 receptor alpha (IL-31RA),[L51159] which is an endogenous cytokine implicated in the pathophysiology
Synonyms: )-IGHJ5*01) [8.8.14] (1-121) -Homo sapiens IGHG2*0, Immunoglobulin G2, anti-(interleukin 31 receptor A) (human-Mus musculus monoclonal CIM331 γ-chain), disulfide with human-Mus musculus monoclonal CIM331 κ-chain, dimerImlifidase
go.drugbank.com/drugs/DB15258ApprovedInvestigationalChronic kidney disease (CKD) is a progressive and irreversible disease that represents a significant burden for both the individual and healthcare system at large. … [A225836,A225921] Imlifidase is a cysteine protease and eliminates Fc-dependent effector functions such as CDC and ADCC by cleaving the heavy chains of human immunoglobulin G (IgG) antibodies.
VB-201
go.drugbank.com/drugs/DB15259InvestigationalVB-201 is under investigation in clinical trial NCT01001468 (Study to Assess VB-201 in Patients With Psoriasis).
Butafenacil
go.drugbank.com/drugs/DB15261ExperimentalButafenacil is under investigation in clinical trial NCT03760328 (Effect of Upper Airway Stimulation in Patients With Obstructive Sleep Apnea).
Categories: Heterocyclic Compounds, 1-RingLesinidase alfa
go.drugbank.com/drugs/DB15267InvestigationalLesinidase alfa is under investigation in clinical trial NCT02324049 (Safety, Pharmacokinetics, and Pharmacodynamics/Efficacy of SBC-103 in Mucopolysaccharidosis III, Type B (MPS IIIB)).
Afabicin
go.drugbank.com/drugs/DB15268InvestigationalAfabicin is under investigation in clinical trial NCT03723551 (Study to Assess Safety, Tolerability and Efficacy of Afabicin in The Treatment of Participants With Bone or Joint Infection Due to Staphylococcus
Categories: Heterocyclic Compounds, 2-Ring