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Brilaroxazine
go.drugbank.com/drugs/DB09226InvestigationalBrilaroxazine (RP5063) is an investigational atypical antipsychotic which is under development by Reviva Pharmaceuticals for the treatment of schizophrenia and schizoaffective disorder. Reviva Pharmaceuticals also intends to investigate ...
Synonyms: 6-(4-(4-(2,3-Dichlorophenyl)-piperazin-1-yl)-butoxy)-2H-benzo(b)(1,4)oxazin-3(4H)-oneCategories: Serotonin 5-HT2 Receptor Antagonists, Serotonin 5-HT2C Receptor AntagonistsMethylene blue
go.drugbank.com/drugs/DB09241ApprovedInvestigationalMethylene blue is an oxidation-reduction agent. The intravenous form of methylene blue is approved by the FDA for the treatment of pediatric and adult patients with acquired methemoglobinemia. Historically, it has been widely used in Afr...
Mixtures: Urin D/S, Uretron D/SCategories: MATE 1 Inhibitors, MATE 2 InhibitorsUbidecarenone
go.drugbank.com/drugs/DB09270ApprovedInvestigationalNutraceutical[A7874] It is a powerful antioxidant, a lipid-soluble and essential cofactor in mitochondrial oxidative phosphorylation. … [L1062] Ubidecarenone is sold as a dietary supplement and is not FDA approved as a drug - it is not meant to treat, cure or prevent any disease.
Mixtures: Complex, ComplexCategories: P-glycoprotein substrates, Electron Transport Chain Complex ProteinsEluxadoline
go.drugbank.com/drugs/DB09272ApprovedInvestigationalEluxadoline is a mixed mu-opioid receptor agonist, kappa-opioid receptor agonist, and a-delta opioid receptor antagonist indicated for use in diarrhea-predominant irritable bowel syndrome (IBS-D). … reduced colonic motility, while antagonism of central delta-opioid receptors results in improved analgesia, making eluxadoline usable for the symptoms of both pain and diarrhea characteristic of IBS-D.
Categories: Heterocyclic Compounds, 1-RingSynonyms: 5-({(4-carbamoyl-2,6-dimethyl-L-phenylalanyl)[(1S)-1-(4-phenyl-1H-imidazol-2-yl)ethyl]amino}methyl)-2-methoxybenzoic acidTenofovir alafenamide
go.drugbank.com/drugs/DB09299ApprovedInvestigationalTenofovir alafenamide is a novel [tenofovir] prodrug developed in order to improve renal safety when compared to the counterpart [tenofovir disoproxil]. … [A178327] Tenofovir alafenamide is indicated to treat chronic hepatitis B,[L6241] treat HIV-1,[L4388,L6277,L6280,L6283] and prevent HIV-1 infections.
Mixtures: GENVOYA ® TABLETAS RECUBIERTAS, DESCOVY® 200MG/10MG TABLETAS RECUBIERTASCategories: Vitamin B Complex, Cytochrome P-450 SubstratesButylscopolamine
go.drugbank.com/drugs/DB09300ApprovedInvestigationalVet approvedButylscopolamine is a peripherally acting antimuscarinic, anticholinergic agent. … It is on the WHO Model List of Essential Medicines, the most important medications needed in a basic health system.
Mixtures: DOLORSIN COMPLEX® TABLETA RECUBIERTA, DOLORSIN COMPLEX® TABLETA RECUBIERTASynonyms: N-butylscopolammonium, N-butylscopolammonium ionSetiptiline
go.drugbank.com/drugs/DB09304ExperimentalSetiptiline is a tetracyclic antidepressant (TeCA) which acts as a noradrenergic and specific serotonergic antidepressant (NaSSA).
Categories: Heterocyclic Compounds, 3-RingPolycarbophil
go.drugbank.com/drugs/DB09311ApprovedWithdrawnPolycarbophil calcium is a synthetic polymer manufactured from the cross-linking of polyacrylic acid with divinyl glycol and a calcium counter-ion. … Polycarbophil calcium is a stool stabilizer used to treat constipation. This drug may also be used to help relieve the symptoms of irritable bowel syndrome or diarrhea.
Categories: Compounds used in a research, industrial, or household settingAlatrofloxacin
go.drugbank.com/drugs/DB09335ApprovedWithdrawnAlatrofloxacin is a fluoroquinolone antibiotic developed by Pfizer, delivered as a mesylate salt. It was withdrawn from the U.S. market in 2001.
Categories: 4-Quinolones, Heterocyclic Compounds, 2-RingPropoxycaine
go.drugbank.com/drugs/DB09342ApprovedPropoxycaine is a local anesthetic of the ester type that has a rapid onset of action and a longer duration of action than procaine hydrochloride [L1588].