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Osunprotafib
go.drugbank.com/drugs/DB21547InvestigationalOsunprotafib is a small molecule drug. The usage of the INN stem '-protafib' in the name indicates that Osunprotafib is a human protein tyrosine phosphatase (HPTP) inhibitor. … Osunprotafib is under investigation in clinical trial NCT04777994 (Study With ABBV-CLS-484 in Participants With Locally Advanced or Metastatic Tumors).
Categories: Heterocyclic Compounds, 1-RingZoracopan
go.drugbank.com/drugs/DB21702InvestigationalZoracopan is a small molecule drug. The usage of the INN stem '-copan' in the name indicates that Zoracopan is a complement receptor antagonist/complement inhibitor. … Zoracopan is under investigation in clinical trial NCT06173596 (A Study to Evaluate Potential Drug Interactions Between ALXN2080 and Itraconazole, Fluconazole & Carbamazepine in Healthy Adults).
9MW3011
go.drugbank.com/drugs/DB24999Investigational9MW3011 is a biologic drug. 9MW3011 is under investigation in clinical trial NCT06752746 (A Study of Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of 9MW3011 in Patients … The drug is an anti-TMPRSS6 (Transmembrane Serine Protease 6, also known as Matriptase-2) monoclonal antibody.[L54591, L54596]
Giloralimab
go.drugbank.com/drugs/DB18862InvestigationalGiloralimab is under investigation in clinical trial NCT04807972 (Study to Evaluate Adverse Events and Change in Disease Activity When Intravenous (IV) Infusion of ABBV-927 Is Administered in Combination … With IV Modified FOLFIRINOX (Mffx) With or Without IV Budigalimab Compared to Mffx in Adult Participants With Untreated Pancreatic Cancer Metastasis).
Synonyms: Immunoglobulin g1, anti-(human cd40 antigen) (human-mus musculus monoclonal pr-1614645 .gamma.1-chain), disulfide with human-mus musculus monoclonal pr-1614645 .kappa.-chain, dimerFominoben
go.drugbank.com/drugs/DB08968ApprovedWithdrawnFominoben is an antitussive agent.
Categories: Heterocyclic Compounds, 1-RingWX-554
go.drugbank.com/drugs/DB21749InvestigationalWX-554 is under investigation in clinical trial NCT01581060 (Phase I/II Dose-escalation Study to Investigate Safety and Pharmacokinetics/ Pharmacodynamics of WX-554 in Patients With Solid Tumours).
Urolithin A
go.drugbank.com/drugs/DB15464ExperimentalUrolithin A is a metabolite of ellagic acid. It has been demonstrated to stimulate mitophagy and improve muscle health in old animals and in preclinical models of aging.[A179494]
Synonyms: Uro-A, Urolithin ACategories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingDeutarserine
go.drugbank.com/drugs/DB19057InvestigationalDeutarserine is under investigation in clinical trial NCT04158687 (A Phase 2 Study to Evaluate the Safety and Efficacy of CTP-692 as an Adjunctive Treatment in Adults With Schizophrenia).
Synonyms: D-serine-2-d