Search

Displaying results 7641 - 7650 of 10000 in total
  1. Drug

    Sulbutiamine

    go.drugbank.com/drugs/DB13416
    Investigational

    The chronic administration of the drug has demonstrated to improve long term memory formation in mice. … It is highly lipophilic, allowing it to cross the blood-brain barrier more easily than other thiamine derivatives.

  2. Drug

    TT-232

    go.drugbank.com/drugs/DB12088
    Investigational

    Tln 232 is under investigation in clinical trial NCT00422786 (Phase II Study of CAP-232 in Patients With Refractory Metastatic Renal Cell Carcinoma).

  3. Drug

    Itepekimab

    go.drugbank.com/drugs/DB16206
    Investigational

    Itepekimab is under investigation in clinical trial NCT03546907 (Proof-of-concept Study to Assess the Efficacy, Safety and Tolerability of SAR440340 (Anti-il-33 Mab) in Patients With Moderate-to-severe

  4. Drug

    Tefibazumab

    go.drugbank.com/drugs/DB16378
    Investigational

    Tefibazumab is under investigation in clinical trial NCT00198289 (Aurexis® in Cystic Fibrosis Subjects Chronically Colonized With Staphylococcus Aureus in Their Lungs).

  5. Drug

    Garivulimab

    go.drugbank.com/drugs/DB16670
    Investigational

    Garivulimab is under investigation in clinical trial NCT03379259 (Study of BGB-A333 Alone and in Combination With Tislelizumab in Advanced Solid Tumors).

  6. Drug

    SYNB1020

    go.drugbank.com/drugs/DB17667
    Investigational

    It was initially designed to convert ammonia to L-arginine [A258838] and granted orphan designation by the FDA for the treatment of urea cycle disorders in August 2016;[L45988] however, the manufacturer … discontinued further development of SYNB1020 to treat hyperammonemia due to a lack of evidence of ammonia-lowering activities by SYNB1020 in a Phase 1b/2a study.

  7. Drug

    Nesvategrast

    go.drugbank.com/drugs/DB19337
    Investigational

    Nesvategrast is under investigation in clinical trial NCT05409235 (Nesvategrast (OTT166) in Diabetic Retinopathy (DR)).

  8. Drug

    Arhalofenate

    go.drugbank.com/drugs/DB11811
    Investigational

    Arhalofenate has been investigated for the treatment of Gout and Hyperuricemia.

  9. Drug

    mRNA-3705

    go.drugbank.com/drugs/DB17668
    Investigational

    mRNA-3705 is an investigational mRNA encoding methylmalonic CoA mutase (MUT) enzyme. Developed by Moderna TX Inc., it is being investigated for the treatment of methylmalonic academia.[A258843]

  10. Drug

    Efdoralprin alfa

    go.drugbank.com/drugs/DB18384
    Investigational

    Efdoralprin alfa is a recombinant human alpha-1 antitrypsin (AAT)-Fc fusion protein.[L54928] It is being investigated as a restorative therapy in adults with AATD emphysema.[L54928]