Search

Displaying results 7641 - 7650 of 10000 in total
  1. Drug

    Malonaldehyde

    go.drugbank.com/drugs/DB03057
    Experimental

    Malonaldehyde is the dialdehyde of [malonic acid].

  2. Drug

    alpha-D-galacturonic acid

    go.drugbank.com/drugs/DB03511
    Experimental

    The α-anomer of D-galacturonic acid.

    Synonyms: α-D-galacturonic acid, α-D-galactopyranuronic acid
  3. Drug

    Lowbush blueberry

    go.drugbank.com/drugs/DB14229
    Investigational

    Ingredient used in over-the-counter medications.

  4. Drug

    Zolazepam

    go.drugbank.com/drugs/DB11555
    ExperimentalVet approved

    Zolazepam is typically used in combination with the NMDA antagonist tiletamine or the α2 adrenoceptor agonist xylazine. … It is around four times the potency of diazepam but it is both water-soluble and un-ionized at physiological pH meaning that its onset is very fast.

    Categories: Heterocyclic Compounds, 2-Ring
  5. Drug

    Calcitonin porcine

    go.drugbank.com/drugs/DB13189
    Experimental

    Calcitonin is a polypeptide hormone secreted by the parafollicular cells of the thyroid gland in mammals. It inhibits bone resorption and lowers both serum and urinary calcium concentrations. … Human calcitonin is available only in very small quantities but has been used in some studies. The first commercially available preparation in Britain was porcine calcitonin (brand name Calcitare).

  6. Drug

    Conteltinib

    go.drugbank.com/drugs/DB21262
    Investigational

    Conteltinib is a small molecule drug. The usage of the INN stem '-tinib' in the name indicates that Conteltinib is a tyrosine kinase inhibitor. … Conteltinib is under investigation in clinical trial NCT06970132 (Study of SY-5933 Plus CT-707 in Advanced Solid Tumors With KRAS p.G12C Mutation).

    Categories: Heterocyclic Compounds, 1-Ring
  7. Drug

    Osunprotafib

    go.drugbank.com/drugs/DB21547
    Investigational

    Osunprotafib is a small molecule drug. The usage of the INN stem '-protafib' in the name indicates that Osunprotafib is a human protein tyrosine phosphatase (HPTP) inhibitor. … Osunprotafib has a monoisotopic molecular weight of 385.15 Da.

    Categories: Heterocyclic Compounds, 1-Ring
  8. Drug

    Seliciclib

    go.drugbank.com/drugs/DB06195
    Investigational

    R-roscovitine (Seliciclib or CYC202) is a cyclin-dependent kinase (CDK) inhibitor that preferentially inhibits multiple enzyme targets including CDK2, CDK7 and CDK9, which alter the growth phase of treated … Developed by Cyclacel, seliciclib is being researched for the treatment of non-small cell lung cancer (NSCLC), leukemia, HIV infection, herpes simplex infection, and the mechanisms of chronic inflammation

    Categories: Heterocyclic Compounds, 2-RingSynonyms: 2-(R)-(1-ethyl-2-hydroxyethylamino)-6-benzylamino-9-isopropylpurine, R-roscovitine
  9. Drug

    Candoxatrilat

    go.drugbank.com/drugs/DB11623
    Experimental

    A dicarboxylic acid monoamide obtained by formal condensation between the amino group of cis-4-aminocyclohexanecarboxylic acid and the cyclopentanecarboxylic acid group of 1-[(2S)-2-carboxy-3-(2-methoxyethoxy … A potent inhibitor of neutral endopeptidase (NEP, neprilysin, EC 3.4.24.11), it is used as its 2,3-dihydro-1H-inden-5-yl ester prodrug in the treatment of chronic heart failure.

  10. Drug

    TAS-102

    go.drugbank.com/drugs/DB08937
    Investigational

    TAS-102 (Taiho Pharma USA, Inc.) is an anti-cancer drug under development and in stage 3 clinical trials for the treatment of colorectal cancer. … It is composed of the thymidine phosphorylase inhibitor (TPI) tipiracil and the cytotoxin trifluridine. Trifluridine inhibits tumor growth by being incorporated into DNA during DNA synthesis.

    Categories: Heterocyclic Compounds, 1-Ring