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Displaying results 7641 - 7650 of 10000 in total
  1. Drug

    Methylmalonic Acid

    go.drugbank.com/drugs/DB04183
    Experimental

    A malonic acid derivative which is a vital intermediate in the metabolism of fat and protein. Abnormalities in methylmalonic acid metabolism lead to methylmalonic aciduria. … This metabolic disease is attributed to a block in the enzymatic conversion of methylmalonyl CoA to succinyl CoA. [PubChem]

  2. Drug

    Phosphoaminophosphonic acid guanylate ester

    go.drugbank.com/drugs/DB02082
    Experimental

    The nucleotide is a potent stimulator of adenylate cyclase. … A non-hydrolyzable analog of GTP, in which the oxygen atom bridging the beta to the gamma phosphate is replaced by a nitrogen atom. It binds tightly to G-protein in the presence of Mg2+.

    Categories: Heterocyclic Compounds, 2-RingSynonyms: Gpp(NH)p, 5'-guanylylimidodiphosphate
  3. Drug

    (1R,2S)-2-Phenylcyclopropanaminium

    go.drugbank.com/drugs/DB02665
    Experimental

    A propylamine formed from the cyclization of the side chain of amphetamine. … This monoamine oxidase inhibitor is effective in the treatment of major depression, dysthymic disorder, and atypical depression. It also is useful in panic and phobic disorders.

    Synonyms: (1R,2S)-tranylcypromine(1+), (1R,2S)-2-Phenylcyclopropanaminium
  4. Drug

    Morrhuic acid

    go.drugbank.com/drugs/DB14087
    Investigational

    Morrhuic acid is a mixture of unsaturated fatty acids obtained from cod liver oil.

    Categories: Compounds used in a research, industrial, or household setting
  5. Drug

    Telotristat

    go.drugbank.com/drugs/DB14218
    Investigational

    A tryptophan hydroxylase inhibitor. [Telotristat ethyl] (brand name Xermelo) is a prodrug of telotristat.

    Categories: Heterocyclic Compounds, 1-Ring
  6. Drug

    AZD-7687

    go.drugbank.com/drugs/DB14949
    Investigational

    AZD-7687 is under investigation in clinical trial NCT01119352 (AZD7687 Multiple Ascending Dose Study).

    Categories: Heterocyclic Compounds, 1-Ring
  7. Drug

    Scriptaid

    go.drugbank.com/drugs/DB17053
    Experimental

    Scriptaid is a histone deacetylase (HDAC) inhibitor researched for its anti-tumor properties.[A253127]

    Categories: Heterocyclic Compounds, 2-RingSynonyms: 1h-benz(de)isoquinoline-2(3h)-hexanamide, n-hydroxy-1,3-dioxo-, N-hydroxy-1,3-dioxo-1h-benz(de)isoquinoline-2(3h)-hexan amide
  8. Drug

    ARCT-810

    go.drugbank.com/drugs/DB17683
    Investigational

    ARCT-810 is an mRNA replacement therapy that delivers ornithine transcarbamylase mRNA to hepatocytes.

  9. Drug

    CSL-689

    go.drugbank.com/drugs/DB17726
    Investigational

    CSL689 is a recombinant fusion protein linking coagulation factor VIIa with albumin (rVIIa-FP).

  10. Drug

    AMT-162

    go.drugbank.com/drugs/DB17922
    Investigational

    AMT-162 is an adeno-associated virus serotype rh10 encoding artificial anti-SOD1 miRNA.