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Displaying results 7651 - 7660 of 10000 in total
  1. Drug

    Icenticaftor

    go.drugbank.com/drugs/DB21466
    Investigational

    The usage of the INN stem '-caftor' in the name indicates that Icenticaftor is a Cystic fibrosis transmembrane regulator (CFTR) protein modulator, corrector, and amplifier. … Icenticaftor is a small molecule drug.

    Categories: Heterocyclic Compounds, 1-Ring
  2. Drug

    Rezivertinib

    go.drugbank.com/drugs/DB21471
    Investigational

    Rezivertinib is a small molecule drug. The usage of the INN stem '-ertinib' in the name indicates that Rezivertinib is a epidermal growth factor receptor (EGFR) inhibitor. … Rezivertinib has a monoisotopic molecular weight of 486.24 Da.

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring
  3. Drug

    Tuxobertinib

    go.drugbank.com/drugs/DB21508
    Investigational

    Tuxobertinib is a small molecule drug. The usage of the INN stem '-ertinib' in the name indicates that Tuxobertinib is a epidermal growth factor receptor (EGFR) inhibitor. … Tuxobertinib has a monoisotopic molecular weight of 560.19 Da.

  4. Drug

    Fipravirimat

    go.drugbank.com/drugs/DB21578
    Investigational

    Fipravirimat is a small molecule drug. The usage of the INN stem '-virimat' in the name indicates that Fipravirimat is a antiviral, disruptor of viral maturation. … Fipravirimat is under investigation in clinical trial NCT04493216 (A Dose-Range Finding Clinical Trial Study in Human Immunodeficiency Virus (HIV-1) Infected Treatment-Naive Adults).

  5. Drug

    Opnurasib

    go.drugbank.com/drugs/DB21583
    Investigational

    Opnurasib is a small molecule drug. The usage of the INN stem '-rasib' in the name indicates that Opnurasib is a Ras protein inhibitor. … Opnurasib has a monoisotopic molecular weight of 525.2 Da.

    Categories: Heterocyclic Compounds, 1-Ring
  6. Drug

    Navarixin

    go.drugbank.com/drugs/DB11711
    Investigational

    Navarixin has been investigated for the treatment of Asthma.

    Categories: Heterocyclic Compounds, 1-Ring
  7. Drug

    Pyronaridine

    go.drugbank.com/drugs/DB12975
    Investigational

    Pyronaridine has been investigated for the treatment of Malaria.

    Categories: Heterocyclic Compounds, 2-Ring
  8. Drug

    Sarcosine

    go.drugbank.com/drugs/DB12519
    Investigational

    Sarcosine has been investigated for the treatment of Schizophrenia.

    Categories: N-substituted Glycines
  9. Drug

    Custirsen

    go.drugbank.com/drugs/DB05487
    Investigational

    Custirsen is also being investigated in the treatment of primary brain tumors. … Custirsen acts as a selective estrogen receptor modulator (SERM), inhibiting the proliferation of estrogen-sensitive breast cancer cells.

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring
  10. Drug

    AZD2315

    go.drugbank.com/drugs/DB06540
    Experimental

    The drug AZD2315, an immunosuppressant developed by AstraZeneca, was in Phase 1 clinical trials for the treatment of rheumatoid arthritis but was discontinued during this phase

    Synonyms: L-ALANINAMIDE, N-(1-OXO-5-PHENYLPENTYL)-L-ALANYL-L-ARGINYL-L-ALANYL-(.ALPHA.S,3R)-3-AMINO-.ALPHA.-METHYL-2-OXO-1-PYRROLIDINEACETYL-L-ALANYL-L-ARGINYL-N-(4-(2-AMINO-2-OXOETHYL)PHENYL)-, ACETATE (1:2), L-ALANINAMIDE, N-(1-OXO-5-PHENYLPENTYL)-L-ALANYL-L-ARGINYL-L-ALANYL-(.ALPHA.S,3R)-3-AMINO-.ALPHA.-METHYL-2-OXO-1-PYRROLIDINEACETYL-L-ALANYL-L-ARGINYL-N-(4-(2-AMINO-2-OXOETHYL)PHENYL)-, DIACETATE