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Displaying results 7671 - 7680 of 10000 in total
  1. Drug

    Ocedurenone

    go.drugbank.com/drugs/DB21519
    Investigational

    Ocedurenone is a small molecule drug. The usage of the INN stem '-renone' in the name indicates that Ocedurenone is a mineralocorticoid receptor (MR, MCR, aldosterone receptor) antagonist. … Ocedurenone is under investigation in clinical trial NCT04968184 (Efficacy and Safety of KBP-5074 in Uncontrolled Hypertension and Moderate or Severe Chronic Kidney Disease (CKD)).

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring
  2. Drug

    Selnoflast

    go.drugbank.com/drugs/DB21522
    Investigational

    Selnoflast is a small molecule drug. The usage of the INN stem '-noflast' in the name indicates that Selnoflast is a inflammasome protein NLRP3 inhibitor. … Selnoflast is under investigation in clinical trial NCT05924243 (A Study to Investigate The Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of RO7486967 in Participants With Early Idiopathic

  3. Drug

    Brimarafenib

    go.drugbank.com/drugs/DB21706
    Investigational

    Brimarafenib is a small molecule drug. The usage of the INN stem '-rafenib' in the name indicates that Brimarafenib is a Raf (rapidly accelerated fibrosarcoma) kinase inhibitor. … Brimarafenib is under investigation in clinical trial NCT04249843 (Study of Safety, Pharmacokinetics, and Antitumor Activity of BGB-3245 in Participants with Advanced or Refractory Tumors).

  4. Drug

    Refanezumab

    go.drugbank.com/drugs/DB14908
    Investigational

    Refanezumab is under investigation in clinical trial NCT00833989 (Safety Escalating Repeat IV, in Stroke Patients).

  5. Drug

    AZD2389

    go.drugbank.com/drugs/DB22104
    Investigational

    NCT06973005: A Study to Investigate How Multiple Oral Doses of AZD2389 Affect the Pharmacokinetics of Midazolam, Caffeine, and Bupropion in Healthy Participants). … AZD2389 is an investigational small molecule inhibitor of fibroblast activation protein (FAP).[L54978] It is currently undergoing safety, tolerability, and PK/PD profiling in clinical trials (e.g.

  6. Drug

    Mongersen

    go.drugbank.com/drugs/DB15019
    Investigational

    Mongersen is under investigation in clinical trial NCT02957474 (A Study to Evaluate the Effect of Food, Formulation Strength, and a Proton Pump Inhibitor on GED 0301 Pharmacokinetics in Healthy Adult Subjects

  7. Drug

    Cepeginterferon alfa-2B

    go.drugbank.com/drugs/DB12814
    Investigational

    Hepatitis C). … Cepeginterferon alfa-2B is under investigation in clinical trial NCT01889433 (An Open-label Comparative Efficacy and Safety Study of Algeron (Cepeginterferon Alfa-2b) in Treatment-naive Patients With Chronic

    Categories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 Enzyme InhibitorsSynonyms: Cepeginterferon Alfa 2 B, Pegylated human interferon A-2B
  8. Drug

    ONO-2952

    go.drugbank.com/drugs/DB14802
    Investigational

    ONO-2952 is under investigation in clinical trial NCT01887002 (Study to Evaluate the Effects of ONO-2952 on Pain Perception Produced by Rectal Distention in Female Subjects With Diarrhea-Predominant Irritable … Bowel Syndrome (IBS-D)).

  9. Drug

    Fianlimab

    go.drugbank.com/drugs/DB18858
    Investigational

    Fianlimab is under investigation in clinical trial NCT06190951 (A Trial to Learn if Fianlimab and Cemiplimab Are Safe and Work Better Than Anti-pd1 Alone in Adult Participants With Resectable Stage 3 or … 4 Melanoma).

    Synonyms: Anti-lag-3 monoclonal antibody regn3767
  10. Drug

    Cofirasersen

    go.drugbank.com/drugs/DB19037
    Investigational

    Cofirasersen is under investigation in clinical trial NCT04441788 (A Study to Assess the Safety, Tolerability, and Efficacy of ION-827359 in Participants With Mild to Moderate Chronic Obstructive Pulmonary

    Synonyms: Dna, d(p-thio)((2'-o,4'-c-((s)-ethylidene))m5rc-(2'-o,4'-c-((s)-ethylidene))m5rc-(2'-o,4'-c-((s)-ethylidene))m5rc-g-a-t-a-g-m5c-t-g-g-t-(2'-o,4'-c-((s)-ethylidene))m5ru-(2'-o,4'-c-((s)-ethylidene))rg-(, -L-MANNOFURANO)M5C-(3'->4')-(2',5'-ANHYDRO-6'-DEOXY-4'-C-(HYDROXYMETHYL)-.ALPHA.-L-MANNOFURANO)M5C-G-A-T-A-