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Miltefosine
go.drugbank.com/drugs/DB09031ApprovedInvestigationalMiltefosine is a broad spectrum antimicrobial, anti-leishmanial, phospholipid drug that was originally developed in the 1980s as an anti-cancer agent. … It is currently the only recognized oral agent used to treat visceral, cutaneous, and mucosal forms of leishmaniasis, a neglected tropical disease.
Categories: P-glycoprotein substratesSynonyms: hexadecyl 2-(trimethylazaniumyl)ethyl phosphateValaciclovir
go.drugbank.com/drugs/DB00577ApprovedInvestigationalValaciclovir (valacyclovir), also known as _Valtrex_, is an antiviral drug that has been used to manage and treat various herpes infections for more than 2 decades. … Valacyclovir is the L-valine ester of aciclovir. It is a member of the purine (guanine) nucleoside analog drug class [F3949].
Categories: Heterocyclic Compounds, 2-RingSynonyms: L-Valine, 2-((2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy)ethyl ester, L-Valine ester with 9-((2-hydroxyethoxy)methyl)guanineTestosterone enanthate
go.drugbank.com/drugs/DB13944ApprovedInvestigationalAs recent as 1 October 2018, the US FDA approved Antares Pharma Inc.' … s Xyosted - a subcutaneous testosterone enanthate product for once-weekly, at-home self-administration with an easy-to-use, single dose, disposable autoinjector [L4659].
Mixtures: NOFERTYL® INYECTABLECategories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesAttapulgite
go.drugbank.com/drugs/DB01574ApprovedVet approvedWithdrawnAttapulgite is a magnesium aluminium phyllosilicate which occurs in a type of clay soil common to the Southeastern United States. … For that reason, it has often been used in antidiarrheal medications. Until 2003, it was the active ingredient used in Kaopectate, before that product was reformulated with bismuth subsalicylate.
Categories: Compounds used in a research, industrial, or household settingFollitropin
go.drugbank.com/drugs/DB00066ApprovedInvestigationalHowever, a more recent study showed there is may be a slight clinical difference, with the alpha form tending towards a higher pregnancy rate and the beta form tending towards a lower pregnancy rate, but … The alpha subunit is glycosylated at Asn 51 and Asn 78 while the beta subunit is glycosylated at Asn 7 and Asn 24.
Synonyms: FSH-a, FSH-bInternational brands: Cinnal-FLatanoprost
go.drugbank.com/drugs/DB00654ApprovedInvestigationalAnother benefit latanoprost is that it can be administered once a day.[A184490] … [A184493] It has been found to be well-tolerated and its use does not normally result in systemic adverse effects like other drugs used to treat elevated intraocular pressure, such as [Timolol].
Synonyms: 5-HEPTENOIC ACID, 7-(3,5-DIHYDROXY-2-(3-HYDROXY-5-PHENYLPENTYL)CYCLOPENTYL)-1-METHYLETHYL ESTER, (1R-(1.ALPHA.(Z),2.BETA.(R*),3.ALPHA.,5.ALPHA.))-, isopropyl (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((3R)-3-hydroxy-5-phenylpentyl)cyclopentyl)-5-heptenoateMixtures: OFTIDON® T SOLUCION OFTALMICA, LATROST-T %0,005+%0,5 GÖZ DAMLASI, ÇÖZELTİ, 2,5 ML 1 ŞİŞEDeutivacaftor
go.drugbank.com/drugs/DB15141ApprovedInvestigationalDeutivacaftor is a small molecule cystic fibrosis transmembrane conductance regulator (CFTR) potentiator.
Categories: Cytochrome P-450 CYP2C8 Inhibitors, Cytochrome P-450 CYP2C9 InhibitorsEugenol
go.drugbank.com/drugs/DB09086ApprovedInvestigationalIt has been used as a topical antiseptic as a counter-irritant and in dental preparations with zinc oxide for root canal sealing and pain control. … Its exact mechanism of action is unknown, however, it has been shown to interfere with action potential conduction.
Categories: Compounds used in a research, industrial, or household settingPotassium hydroxide
go.drugbank.com/drugs/DB11153Approved[L1946,L1951] This ingredient has been considered as generally safe as a direct human food ingredient by the FDA, based upon the observance of several good manufacturing practice conditions of use. … Recently, it has been studied for efficacy and tolerability in the treatment of warts.
Mixtures: Tincture Green, Tincture Green SoapCategories: Compounds used in a research, industrial, or household settingTick-borne encephalitis vaccine (whole virus, inactivated)
go.drugbank.com/drugs/DB16611ApprovedInvestigationalhas been carried out in CEF cells only. … [A237505, A237520] While some patients recover fully following neurological TBE, neurological sequelae can last for years and rare chronic forms of the disease have also been noted.